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Pegcetacoplan: A breakthrough treatment for dry age-related macular degeneration?

12 February 2025 | | EYE - Pathology, EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is a degenerative condition affecting the macula, the part of the retina responsible for central vision. It is characterised by the presence of drusen and retinal pigment epithelium (RPE) abnormalities in the absence of other macular...

In conversation with Marc Labetoulle

9 December 2024 | | EYE - Cornea
Following the hugely successful 10th Tear Film & Ocular Surface Society (TFOS) 2024 Conference which took place in Venice, Italy between 30 October – 2 November, we managed to have a quick Q&A with presenting attendee, Marc Labetoulle. Delivering his...

Lessons from an unusual case of syphilis

3 August 2023 | | EYE - Vitreo-Retinal
The rise of syphilis transmission rates over the past two decades has been one of public health’s great puzzles. In the UK, the situation has reached epidemic levels, with a 126% increase between 2013 and 2018 [1]. We present a...

VISION 2020 LINKS: COECSA Fellowship examination goes from strength to strength

1 April 2019 | | EYE - General
Eye health problems and access to diagnosis and treatment is an important issue throughout low- and middle-income countries (LMICs), and particularly on the African continent, where quality of life is drastically affected by poor vision, blindness and deteriorating eye health,...

Building capacity for diabetic retinopathy services in Malawi

1 August 2019 | | EYE - Vitreo-Retinal, EYE - General
Screening for diabetic retinopathy prevents blindness. There is no systematic screening programme for diabetic eye disease in Malawi and people present when they have lost vision and it is too late for treatment. The aim of the VISION 2020 LINK...

SOS (Simplified Ophthalmic Statistics) Part 2: How to summarise your data and why it’s a good idea to do so

1 August 2018 | | EYE - General
Studies involve capturing data. Statistical techniques allow data to be used to answer important research questions. A case series may have data on a handful of subjects but we are now entering the Big Data arena where datasets can be...

Effective management of dry eye and ocular surface disease

4 August 2021 | | EYE - General
Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...

The role of aspirin in the treatment of NAION: Benefits and controversies

4 December 2024 | | EYE - Neuro-ophthalmology
Non-arteritic anterior ischaemic optic neuropathy (NAION) is the most common acute optic neuropathy in individuals over 50 with estimated prevalence of 2–10 per 100,000 people, characterised by sudden, unilateral vision loss due to ischaemic injury to the optic nerve head....

Effect of minor trauma in eyes with previously undiagnosed angioid streaks

1 April 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Angioid streaks (AS) may be associated with pseudoxanthoma elasticum (PXE), Paget’s disease, haemoglobulinopathies, Ehlers-Danlos Syndrome or abetalipoproteinaemia. Histopathology showed retinal pigment epithelium (RPE) and choriocapillaris loss, elastic fibre degeneration, calcium deposition, active choroidal neovascular membrane (CNVM) and vascular endothelial growth...

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

1 February 2017 | | EYE - Vitreo-Retinal
There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

VISION 2020 LINKS Programme: the Madagascar-Leeds LINK

1 December 2014 | | EYE - Cataract, EYE - Cornea, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal, EYE - General
Madagascar is a fascinating and culturally rich island which has an ‘exotic’ status in most people’s eyes. Yet it is among the poorest countries in the world. According to the World Bank, 92% of the population live on less than...

Hot debates in medical retina and imaging: Perspectives from the Controversies in Ophthalmology 2020 virtual conference

5 August 2020 | | EYE - Vitreo-Retinal, EYE - Imaging, EYE - General
Controversies in medical retina and imaging were debated during the Controversies in Ophthalmology 2020 virtual conference held during two mid-day scientific sessions on 27 and 28 March 2020. The author recounts key perspectives and presents viewpoint recommendations from the Vision...