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Retinoblastoma mortality associations with choroidal and optic nerve invasion
The authors present a retrospective cohort study. Data was extracted from the National Cancer Institute’s Surveillance Epidemiology and End Results (SEER) database, based in the US and founded in 1973. Cases of retinoblastoma were extracted using the inclusion criteria of...
Referral patterns and pathways for intracranial hypertension
The authors present a retrospective case review of individuals with suspected raised intracranial pressure (ICP) over a 12-month period a single tertiary neuro-ophthalmology centre. Cases were categorised into four groups based on examination by neuro-ophthalmology; 1) referred after identification of...
Homonymous hemianopia due to stroke presenting symptoms and lesion locations
A retrospective case notes review was undertaken of patients diagnosed with homonymous hemianopia following a radiologically confirmed stroke. A total of 85 patients were identified by searching an electronic medical records system over an 11-year period. Data were extracted from...
Septo-optic dysplasia – a case note review
Septo-optic dysplasia (SOD) is a congenital disorder belonging to the midline brain malformation group. The condition manifests as a classical triad, including optic nerve hypoplasia (ONH), agenesis of midline structures (absent septum pel-lucidum and agenesis of the corpus callosum), and...
Comparison of paediatric migraine and healthy controls using optical coherence tomography angiography
The authors present a cross-sectional study which recruited patients with paediatric migraine without aura along with age and sex-matched healthy controls. Both groups were recruited following attendance to an ophthalmology outpatient clinic. Children diagnosed with any of the following were...
Could idebenone by the solution for treating dominant optic atrophy?
Dominant optic atrophy (DOA) is a disease of the retinal ganglion cells, with no current treatment options. In most cases, DOA is caused by a mutation in the OPA1 gene. The aim of this study was to evaluate the effect...
Being more consistent with screening for convergence insufficiency
This prospective cases series aimed to identify the average values and sensitivity of clinical measurements of convergence to aid diagnosis of convergence insufficiency (CI). Children and adults presenting over a two-year period with symptoms including diplopia when reading, headache with...
App usage to improve compliance with amblyopia therapy
In this study, the authors report the development of the software ‘Magical patching’ for iOS and Android (for smartphones and tablets) as the first version of the amblyopia treatment Chulalongkoru university (ATCU) app. In this randomised controlled trial, they aimed...
Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs
The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...
Comparing retinal thickness in Parkinson’s disease, essential tremor and healthy controls
This study aimed to compare retinal findings in chronic essential tremor (ET), early Parkinson’s disease (PD) and healthy controls. Those recruited with ET had to have received a diagnosis a minimum of three years previous and those with PD had...
Beyond ‘Shield and Ship’: a novel device (Eye-Aid) to provide temporary aqueous tamponade
The authors present a pilot efficacy study of the novel Eye-Aid device in a porcine model of full-thickness corneal wounds to mitigate anterior chamber collapse in the forward military environment. Currently, the ‘Shield and Ship’ paradigm taught to military healthcare...
