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1696 results found

Eye disorders occurring in congenital CMV

The aim of this study was to examine the relationship between congenital cytomegalovirus (CMV) infection and ophthalmological disorders that occur in children and record the frequency and type of eye disorders that occur from the infection. Of 449 potential studies,...

Cataract progression after Nd-YAG laser iridotomy in primary angle-closure suspect eyes

A total of 889 of eligible bilateral primary angle-closure suspect (PACS) patients were recruited from the Zhongshan Angle Closure Prevention Trial. One randomly selected eye received laser peripheral iridotomy (LPI), while the fellow remained untreated. Cataract was graded by the...

Tocilizumab in Graves’ orbitopathy

This prospective European study looks at the response to tocilizumab in corticosteroid-resistant disease. Tocilizumab (TCZ) is a monoclonal antibody that competitively inhibits IL-6 binding to its receptor. Unlike teprotumumab, the advantage of TCZ is that it is already used within...

Features of branchio-oculo-facial syndrome

Branchio-oculo-facial (BOF) syndrome is an autosomal dominant inherited syndrome that typically presents with branchial cleft sinus defects, ocular anomalies and dysmorphic facial appearance. The authors present a new case alongside the results of a literature review describing the common genetic...

BTA injection to treat convergence insufficiency

The outcomes of patients with convergence insufficiency (CI) treatment with botulinum toxin A (BTA) in one or both lateral rectus muscles are reported. This was a retrospective study of 23 patients; eight males, 15 female, mean age 59 years (range...

Clinical predictors of proliferative sickle cell retinopathy

Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...

Transsynaptic retrograde degeneration linked to homonymous visual field loss after stroke

centre, of individuals identified with homonymous visual field loss post ischaemic stroke. Exclusion criteria were bilateral ischaemia, anterior / pregeniculate visual pathway affected and other pathology with the potential to effect visual fields. The following were extracted from the medical...

Retrobulbar amphotericin B for rhino-orbital-cerebral mucormycosis

Rhino-orbital-cerebral mucormycosis (ROCM) is a rare and often fatal infection usually occurring in immunocompromised patients from diseases such as diabetes, haematological malignancy and solid organ transplantation. Current standards of care include systemic antifungal therapy and debridement, including exenteration. This study...

Female participation at the AAO conference

This study sought to understand whether female participation among paediatric ophthalmologists at the American Academy of Ophthalmology (AAO) annual meeting resembles the sex distribution of the field as well as whether the Covid-19 pandemic significantly affected female involvement. From 2018–2022,...

Use of Leflunomide as a treatment for paediatric chronic uveitis

Leflunomide is a disease modifying anti-rheumatic drug approved for treatment of rheumatoid arthritis and psoriatic arthritis in adult patients. This study reports five illustrative case reports of children using Leflunomide as an adjunct treatment with anti-tumour necrosis factor (TNF) agents...

Paediatric ophthalmology five-year results of atropine 0.01% efficacy in the myopia control in a European population

This a prospective, randomised and longitudinal study from Madrid, Spain in 361 eyes from 361 children randomised into the control group (177 eyes with no treatment) and the treatment group (184 eyes with 0.01% atropine drops once daily). Complete eye...

Vigabatrin-induced retinal toxicity detected by 30Hz ERG

The purpose of this study was to assess the role of 30Hz flicker electroretinogram (ERG) as a marker for measuring changes in visual function over time in children receiving vigabatrin. This was an observational study of 11 children with mean...