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Methotrexate and mycophenolate mofetil for non-infectious uveitis
This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...
LASEK vs. epi-LASIK for myopia: meta-analysis
Previous studies have produced inconsistent conclusions on the relative benefits between LASEK vs. Epi-LASIK. LASEK uses 20% alcohol to separate an epithelial flap from the Bowman membrane. After ablation, the epithelial flap is repositioned onto the cornea. Epi-LASIK creates the...
Diagnosis of amiodarone-associated optic neuropathy
Amiodarone is a widely used anti-arrhythmic drug. Several case reports describe optic neuropathy which has been linked to its use. This case series discusses the diagnosis of amiodarone-associated optic neuropathy (AAON) and its potential impact on cardiac therapy. The authors...
Diagnosis and management of orbital vascular malformations
This is an authoritative review of a controversial and difficult clinical area. The authors have experience of over 350 cases and provide a well-structured review of the classification and management of orbital vascular malformations. They emphasise the need to understand...
Clinical and neuro-ophthalmologic predictors of visual outcome in idiopathic intracranial hypertension
This prospective study of 40 patients aims to assess visual morbidity in patients with idiopathic intracranial hypertension (IIH). Final visual outcome of patients was compared with clinical and neuro-ophthalmic parameters such as visual acuity, visual field, contrast sensitivity, retinal nerve...
Uveitis in the elderly
This study from Turkey evaluated the causes and clinical characteristics of uveitis in elderly patients. Data from 90 eyes of 68 patients aged 60 years and older were reviewed. Anterior uveitis was present in 75% (33% of these had keratouveitis),...
Prediction of visual outcome in IIH
In this prospective study, visual outcome of 40 patients with idiopathic intracranial hypertension (IIH) was compared with clinical and neuro-ophthalmic parameters. The purpose of this was to determine any correlation to try and predict visual outcome for IIH patients. Parameters...
Using graphical illustration to predict giant cell arteritis
A nomogram is a chart or graph of scaled variables that facilitates the approximate computation of a mathematical function via intersecting lines. The objective of this study was to illustrate the use of a nomogram for the prediction of giant...
Orbital cellulitis outcomes for children
This paper discusses the clinical profile and multidisciplinary team (MDT) management outcomes in children treated for paediatric orbital cellulitis. This was a prospective study of 40 children with a mean age of 7.5 years (4-12). Unilateral orbital cellulitis cases had...
Correlation of parent observations vs. clinical measures of exotropia
The purpose of this study was to compare the parental observations with the clinical evaluation findings in paediatric patients with intermittent exotropia and to determine the clinical factors associated with the parental observations. The study included 100 parents of 95...
Clinical outcomes of endoscopic dacryocystorhinostomy
The aim of this study was to report the authors’ experience with endoscopic dacryocystorhinostomy (ED) in a paediatric population and to evaluate the effect of surgical site reassessment on anatomy and clinical outcomes. The study included 47 children <18 years...
