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Systemic anti-inflammatory versus fluocinolone acetonide intraocular implant
In the Multicenter Uveitis Steroid Treatment (MUST) trial, 255 patients with intermediate uveitis, posterior uveitis or panuveitis were randomised to either fluocinolone acetonide intraocular implant or systemic corticosteroid therapy which was supplemented with immunosuppression if required. Patients were followed up...
PD-1 and retinal ganglion cell death
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
IOL cataract surgery in seven to 24 month olds
The purpose of this study was to present the long-term outcome of IOLs in paediatric patients who received cataract surgery aged seven to <24 months. This was retrospective study with minimum follow-up of 12 months for 27 patients (28 eyes)....
Conversion factors for fovea on / off detachments
This is a retrospective study of medical records in a single unit over a 14 year period from January 2001 – December 2014, of patients who converted from fovea-on to fovea-off rhegmatogenous retinal detachment (RRD). Ten cases were identified while...
Same day air bubble removal after DSEK/DSAEK
A complete air removal on same day as descemet’s stripping endothelial keratoplasty (DSEK/DSAEK) leads to prompt restoration of the anterior chamber and thus has been hypothesised to assist with the recovery of endothelial function and promote graft adhesion. The results...
Positive diagnosis of acute posterior ischaemic optic nerve neuropathy
Posterior ischaemic optic neuropathy is a rare cause of visual loss believed to be due to infarction in the territory of the pial branches of the ophthalmic artery. There is an absence of clinical signs which means the diagnosis is...
Cataract surgery and circadian photoentrainment
The study authors sought to investigate the possible effects of circadian photoentrainment following cataract. This was a randomised clinical trial, where 76 eyes of 76 patients (with bilateral cataract) were randomised to blue-blocking or neutral intraocular lenses (IOLs). Outcome measures...
γδ T cell depletion does not affect fungal keratitis
Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...
A case of progressive supranuclear palsy-like syndrome following aortic aneurysm repair
This original article illustrates the case of an 18-year-old woman who developed progressive supranuclear palsy-like syndrome following an uneventful aortic aneurysm repair. The patient was unaffected for the first 48 hours after surgery and then developed dysarthria, dysphagia (requiring a...
A case series of acute visual loss following excessive alcohol and / or drug use
This study presents three cases of so called Saturday night retinopathy, an acute visual loss following intravenous drug abuse and stupor, leading to continuous pressure on the orbit while asleep. All three cases presented with acute vision loss and had...
Dyslexic reading improved by vergence training
The aim of this study was to evaluate if reading performance could be improved by a period of compensatory vergence training in dyslexic children with otherwise normal binocular vision. The study included 13 children with dyslexia – mean age of...
