This is a retrospective analysis of three patients who underwent mini DMEK for massive corneal hydrops in acute keratoconus. DMEK graft was trephined or trimmed according to the size and the shape of the gap in the patient’s Descemet membrane...
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...
The authors present the first case report in which a mini (reduced diameter) Descemet’s stripping automated endothelial keratoplasty (mini-DSAEK) has been used to manage a traumatic corneal perforation. A 69-year-old male presented with 6/36 best spectacle-corrected visual acuity (BSCVA) and...
Vision research presentations and publications explore practice considerations in the management of AMD and diabetic retinopathy. Over the past two decades in Europe there has been a decreasing prevalence of age-related macular degeneration (AMD) and an improvement in visual acuity...
The management of neovascular age-related macular degeneration (nAMD) has advanced dramatically over the past seven years, with the introduction of targeted new therapies that successfully maintain or improve vision in a majority of affected individuals. It’s a fast moving field,...
“Life is either a daring adventure, or nothing at all” – Helen Keller, deafblind American author, activist, and disability rights advocate I have always had a thirst for adventure, even if it has been predominantly from the comfort of my...
Informed consent is a cornerstone of ethical and legal practice in healthcare, particularly in fields like ophthalmology where specialised interventions can have significant implications for a patient’s vision and quality of life. In the UK, informed consent is not merely...
The aim is to present a case of neurofibromatosis type-1 (NF-1), also known as von Recklinghausen disease, who presented with bilateral multiple choroidal nodular nevi following chemotherapy and mastectomy for breast cancer. Neurofibromatosis type-1 presents as a wide range of...
When people ask me what life in the laboratory is really like, I often pause. On one hand, it is the romantic notion of pushing back the boundaries of science with the daily rhythm of experiments, data and easily obtained...
“Alright, this is where our future lies Rodney. Second hand motors. This time next year we’ll be millionaires.” The above is the well-known quote by the happy-go-lucky Del Boy from the famous British sitcom, Only Fools and Horses, forever on...