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Association between serum levels of testosterone and estradiol with meibomian gland assessments in postmenopausal women
This study aims to reveal any correlation between serum levels of testosterone and estradiol in postmenopausal women with meibomian gland dysfunction. Postmenopausal subjects were defined as amenorrhoea for at least one year with low follide stimulating hormone (FSH) and estradiol....
Effects of orbital decompression
This is a retrospective review of 319 orbital decompression operations in 169 patients (73% female) with thyroid eye disease. Three wall decompressions were performed in 92 eyes, 2-wall in 206 (medial and floor), and a single wall (medial) in 18,...
Lateral canthal position after lateral orbitotomy
This is a retrospective photographic study of changes in the lateral canthal position following a lateral orbitotomy performed via a lateral canthotomy and cantholysis of both upper and lower limbs of the lateral canthal tendon. Reconstruction of the lateral canthus...
Sex differences in the relationship between obesity and choroidal nevus in US adults
The National Health and Nutrition Examination Survey (NHANES); a population-based survey conducted annually in the US by the Centers for Disease Control and Prevention, was used to identify populations at higher risk for choroidal naevus. Over a period of four...
Development of testing protocols for high and low contrast visual acuity
Dysfunction of the afferent visual system, characterised by impairments in high-contrast visual acuity (HCVA) and low-contrast visual acuity (LCVA) have been demonstrated in some neurological conditions such as multiple sclerosis and Parkinson’s disease. HCVA and LCVA are also potential quantitative...
IAC vs. IVC chemotherapy for RB
This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...
Systemic pharmacology of intravitreal anti-VEGF
This study aimed to evaluate and compare serum drug concentrations and plasma free-VEGF concentrations in patients with AMD, DME, or RVO receiving intravitreal injections of aflibercept, bevacizumab or ranibizumab. This prospective study enrolled patients from several offices of a single...
Outcomes of cataract surgery in patients with uveitis
This is a systematic, evidence-based literature review and meta-analysis, looking at the visual outcomes (vision 20/40 or better) of cataract surgery in uveitic eyes. The authors searched MEDLINE, EMBASE, CINHAL and CENTRAL, including English language and human studies only. They...
Long-term corneal crosslinking results in paediatric eyes
This prospective longitudinal study examined patients 18 years of age or less with progressive keratoconus, who underwent corneal crosslinking and completed 10 years of follow-up. Crosslinking protocol involved removal of epithelium, 10 minutes of riboflavin soaking, followed by 30 minutes...
Automated grading of diabetic retinopathy: is it possible?
Diabetic retinopathy (DR) is a frequent microvascular complication of diabetes and a leading cause of blindness worldwide. However, much of this diabetic blindness can be delayed or even prevented with timely diagnosis and proper treatment. For this reason, regular screening...
Differences of the anterior segment parameters in children with Down syndrome
This cross-sectional study was designed in order to demonstrate the differences in anterior segment parameters in children with trisomy 21. This is important as it may impact on surgical planning when undertaking procedures in the anterior segment such as corneal...
