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Why is there subretinal fluid at the macula?
This is a review article looking at the differential diagnosis of subretinal fluid in the macula that could be diagnosed as central serous chorioretinopathy (CSCR). The authors have categorised them into 12 groups: neovascular diseases, vitelliform lesions, inflammatory diseases, ocular...
Do patients with prolactinomas using dopamine agonist drugs have autonomic dysfunction?
This prospective study aimed to determine whether there is autonomic dysfunction in patients with prolactinomas using dopamine agonist (DA) drugs by measuring static and dynamic pupillary responses using an automatic pupillometric device.Included were 25 eyes from 25 patients who were...
Natural history of idiopathic intracranial hypertension depending on incidental or symptomatic presentation
The authors present a large retrospective review cohort of consecutive patients diagnosed or presumed idiopathic intracranial hypertension (IIH) over a three-year period at a single tertiary centre. Patients on medication with a known aetiology for IIH were excluded. The cohort...
Local surgical treatment of trigeminal neuralgia
This is a retrospective review of a new surgical treatment of intractable periorbital neuropathic pain. Five patients with post-herpetic (three), post-traumatic (one) and idiopathic (one) neuralgia underwent transection of the nerves supplying the dermatomes affected by the neuropathic pain. The...
Transfected RPE cells inhibit AMD in rats
Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...Prevalence of acute anterior uveitis in diabetic patients attending diabetic eye disease clinics
The authors share their investigation at Manchester Royal Eye Hospital into the association between diabetes and AAU. The global prevalence of diabetes mellitus (DM) is rapidly rising from an estimated 9.3% in 2019 to 10.2% by 2030 [1]. The link...Acute retinal necrosis presumably caused by Epstein-Barr virus infection
Acute retinal necrosis (ARN) is an uncommon, but serious and potentially blinding condition. ARN is characterised by panuveitis, occlusive vasculopathy and progressive peripheral necrotising retinitis. The diagnosis is clinical but confirmation is sought via aqueous and vitreous sampling. Varicella zoster...
Ophthalmology Lecture Notes (Twelfth Edition)
During medical school, our seniors often told us that the easiest way to remember something is to understand it. And rightly so, when I came across the Ophthalmology Lecture Notes textbook as a student I realised that the key to...
