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276 results found

Bilateral internuclear ophthalmoplegia

Bilateral internuclear ophthalmoplegia (INO) has been linked with various pathological conditions of the central nervous system such as multiple sclerosis, stroke, tumours and brainstem inflammatory processes. This unusual case report describes a case of a 45-year-old female patient presenting with...

A case report of visual loss as a consequence of coeliac disease

The authors present a case of permanent visual loss secondary to occipital lobe calcification in coeliac disease, the first reported such case. The 58-year-old man had been diagnosed with coeliac disease 20 years prior to his visual investigations and had...

Rare case reports of benign optic glioma in adults with clinically aggressive nature

Primary optic nerve gliomas are most commonly benign and occurring in childhood. Malignant optic gliomas occur in adulthood and follow an aggressive course usually leading to blindness and death within months. This paper describes the clinical and histopathological features of...

An unusual case of sellar chondroma

A single case of chondrogenic neoplasm arising from the base of the skull is presented and discussed. These benign and slow growing tumours in the sellar region are extremely rare and as such this article provides a useful insight and...

Diabetic retinopathy and body fat distribution and adipokine secretion in type 2 diabetics

The major risk factors for diabetic retinopathy (DR) in patients with diabetes are poor glycaemic or blood pressure control, duration of diabetes and nephropathy related to the severity of DR. Several studies suggest that DR is associated with visceral fat...

Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience

Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...

EP in a case of abducens nerve palsy

Ecchordosis physaliphora (EP) is a rare non-malignant mass that originates from remains of the notochord and is typically asymptomatic. Symptomatic cases are extremely rare, and the majority are managed by surgical resection. This case study reports a 42-year-old male who...

Knobby eye syndrome

This study used high resolution MRI to demonstrate and evaluate globe shape in axial high myopia and identify and characterise those with prominent equatorial staphylomata that deflect extraocular muscle paths and presumably alter motility patterns in strabismus. The study included...

Radiotherapy for orbital apex cavernous haemangiomas

This is a review of six patients with cavernous venous malformations (haemangiomas) involving the orbital apex who were treated with fractionated stereotactic radiotherapy. Patients were diagnosed on MRI imaging with only one having had previous surgery to debulk the lesion....

Brain abnormality as risk factor for consecutive exotropia

The authors evaluated and compared the cerebral MRI findings in operated infantile esotropia cases with and without consecutive exotropia. This was a retrospective study of 28 patients. Group 1 had 17 cases of consecutive exotropia with a mean follow-up of...

New prognostic model for multiple sclerosis after optic neuritis presentation

The authors present a post-hoc analysis using the publicly available data set from the Optic Neuritis Treatment Trial. The Cox proportional hazards regression models were used to assess for associations between clinical and radiological variables and the development of clinical...

Computer-assisted surgery in the orbit

In this paper the authors describe the growing use of computer-assisted surgery in ophthalmology. It is already described as a powerful adjunct in neurosurgery and sinus surgery and here they describe their experience of using it for the orbit; specifically...