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Review of pathogenesis of Acanthamoeba keratitis

4 February 2021 | | EYE - Cornea, EYE - General
In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...
American Journal of Ophthalmology cover image.

Sarcoid uveitis and its systemic associations

1 October 2021 | | EYE - Vitreo-Retinal
This retrospective cross-sectional study examined systemic associations of sarcoid uveitis and association with uveitis clinical phenotype and ethnicity. Three hundred and sixty-two subjects with either definite or presumed sarcoid uveitis were identified and included in the study. Any subject with...
Neuro-ophthalmology front cover image.

Retrospective review of visual outcomes in Idiopathic intracranial hypertension (IIH)

1 December 2022 | | EYE - Neuro-ophthalmology | Idiopathic intracranial hypertension, Pseudotumor cerebri, visual outcome
Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. IIH is diagnosed by the modified Dandy criteria, which include normal neuroimaging and cerebrospinal fluid (CSF) composition, high CSF opening...
Neuro-ophthalmology front cover image.

Visual prognosis in Irish Leber’s hereditary optic neuropathy

1 December 2022 | | EYE - Neuro-ophthalmology | Leber’s hereditary optic neuropathy, idebenone, inherited optic neuropathy, mtDNA, ophthalmic genetics, optic atrophy
Leber’s hereditary optic neuropathy (LHON) is an inherited optic neuropathy This paper presents a retrospective review of clinical data from patients with LHON presenting to an Irish tertiary referral ophthalmic hospital. Clinical and genetic characteristics were assessed for useful biomarkers...

Leber’s hereditary optic neuropathy outcomes in an Indian population

4 October 2023 | | EYE - Paediatrics, EYE - Strabismus
A large cohort study in an Indian population is presented, with clinical and genetic profile analysis of patients with Leber’s hereditary optic neuropathy (LHON) treated over a five-year period. The study included 157 patients; 143 male, 14 female (10.2:1 ratio)...
Pediatric Ophthalmology & Strabismus journal cover

Combined home and office-based treatment for accommodative insufficiency

1 September 2025 | | EYE - Paediatrics
The purpose of this study was to evaluate the effect of the Bernell EYEPORT II vision training system on accommodation in cases of accommodative insufficiency (AI). This was a prospective randomised study comparing the intervention of the EYEPORT II vision...

Burnout: ubiquitous and unavoidable?

3 August 2023 | | EYE - General
Meriam Islam reminds us of the importance of ‘putting our oxygen mask on first’ and avoiding burnout while we progress through our careers. Burnout. It’s a term we hear a lot. What does it mean though? According to Merriam Webster,...

Free rail travel for blind and partially sighted people and their companions announced for Scotland

8 April 2024 | charity, Sight Scotland, UK, Scotland, sight loss, government
Leading sight loss charities have hailed the Scottish Government’s ‘life changing’ decision to provide free rail travel for blind and partially sighted people and their companions, saying this decision will enhance rehabilitation, independence and ensuring people with vision impairment can maintain links with their communities.

Glaucoma-NET: a novel way of improving glaucoma management in sub-Saharan Africa

1 June 2022 | | EYE - Cornea, EYE - General
Background Glaucoma is the second most common cause of blindness worldwide [1]. People with untreated glaucoma suffer from irreversible, progressive loss of sight. The disease is characterised by progressive loss of visual field, with pathological cupping of the optic disc...

OBITUARY: A short tribute to Mike Sanders, Neuro-ophthalmologist

3 October 2022 | | EYE - Neuro-ophthalmology
Mike Sanders was Consultant Neuro-Ophthalmologist at St Thomas’ Hospital and the National Hospital, Queen Square in London, 1969 to 1999. He passed away on 25 July of this year. Over this 30-year period he had huge influence over the evolution...

Photophobia: an unusual symptom of a pituitary macroadenoma

2 February 2024 | | EYE - General
Introduction Photophobia, defined as ‘an abnormal intolerance to light’, is commonly associated with a range of both ocular and neurological pathologies such as dry eye, blepharospasm, corneal pathologies, cataracts, uveitis, retinal dystrophies, optic neuritis, migraine, meningitis, and traumatic brain injury...

Headaches in ophthalmology (part 1)

1 October 2018 | | EYE - Neuro-ophthalmology, EYE - General
Ophthalmologists see a large number of patients with headaches or facial pain in the ophthalmic outpatient clinics or in emergency clinics. Over two articles, I will discuss several causes of headaches, ocular manifestations and proposed management and referral options. It...