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Anterior segment imaging: a photographer’s view
My name is Rosalyn Painter and I work within the vision science and ophthalmic imaging team at Bristol Eye Hospital, where we cover all aspects of imaging within the hospital, including fluorescein angiograms, fundus photography, optical coherence tomography (OCT), slit-lamp...Inhibiting high-risk corneal allografts
1 October 2014
| Graham Wallace
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EYE - Cornea, EYE - General
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T regulatory cells, Tim-1, high-risk corneal allograft rejection, mice
The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...
Outcomes for congenital vs. developmental cataract surgery
This study retrospectively reviewed follow-up data (minimum one year) to evaluate ocular outcomes and the potential factors affecting visual acuity after foldable intraocular lens (IOL) implantation in preschool childhood (up to six years) with bilateral cataract. The study included 43...Exploiting nature’s randomised trials of eye disease
1 December 2022
| Skanda Rajasundaram, Dalia Abdulhussein, Christopher Bentley (Prof), Shafi Balal, Minak Bhalla
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EYE - Glaucoma, EYE - Vitreo-Retinal, EYE - Orbit
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...
Silicone oil migration presenting as an eyelid cyst
The author presents a single case report of a rare complication of silicone oil tamponade, silicone oil migration, after pars plana vitrectomy. A seven-year-old female, with a history of vitrectomy one year prior for penetrating eye trauma, presented with a...An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs
1 December 2016
| Stacey Strong, Michel Michaelides (Prof)
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EYE - Vitreo-Retinal
Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...
The art of giving generous grains
3 April 2024
| Rahila Bashir
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EYE - General
On the drive home, after a long day of eye screening patients in homeless shelters, I would pass through the boroughs, towns and villages of east London. Stopping at the soup kitchen, I would meet Christian with heavy cataracts, and...
Diabetes and diabetic retinopathy: Changes in understanding of the disease over the last 25 years and how the UK is helping low-income countries tackle the challenges
1 June 2018
| Marcia Zondervan, Covadonga Bascaran, Frank Sandi, Chloe Cornes, Pippa Williams
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EYE - Vitreo-Retinal, EYE - General
Diabetes – a historical perspective Diabetes mellitus (DM) is a chronic disease caused by inherited and / or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. Such a deficiency results in...
Developments in oculoplastic surgery
1 June 2018
| Rod McNeil
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EYE - Oculoplastic
A study of NHS practice demonstrated significant patient-reported quality-of-life improvements from commonly performed oculoplastic operations: entropion repair, ectropion repair, ptosis repair and dacrocystorhinostomy (DCR) [1]. In recent years, surgical and non-surgical approaches to functional and aesthetic oculoplastic surgery have advanced...
FAQs about cerebral visual impairment (CVI): identifying and helping those affected
2 August 2022
| Gordon N Dutton
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EYE - General
Cerebral visual impairment is common in both adults and children, yet the diagnosis can easily be missed unless one is tuned into the presenting features. This article provides a succinct introduction to this important topic. What is vision? Vision is...
Community Eyecare Services in Northern Ireland: putting the patient at the centre, improving outcomes and maximising system resource
1 August 2017
| Raymond Curran
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EYE - General
The UK has four healthcare systems; Northern Ireland, Scotland and Wales each has autonomous legislature that develops health policy, while the UK government directly runs England’s NHS. Like the other nations, Northern Ireland is continually challenged to meet the needs...