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Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs

The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...

Horizontal recti injection of botulinum toxin for treatment of infantile nystagmus

In this study the authors aimed to demonstrate the effect of botulinum toxin (BT) on the frequency of ocular oscillation in children with infantile nystagmus syndrome (INS). Botulinum toxin was administered with direct injection into the horizontal recti muscles using...

Comparison of surgical procedures for third cranial nerve palsy with large-angled exotropia

The authors present a retrospective case review with the aim to compare two surgical procedures. Cases were operated on at a single centre, by a single surgeon, over a 14-year period. The inclusion criteria were cases with congenital or acquired...

Anti-VEGF agents treatment outcomes in macular telangiectasia

This article is a review of a systematic literature search on Ovid MEDLINE, Embase, and Cochrane Library, from inception to June 2024 for comparative studies on anti-VEGF agents in macular telangiectasia (MacTel). The primary outcome was the change in best-corrected...

Feasibility and acceptability of virtual reality visual field testing compared to standard perimetry

The authors present a prospective pilot study which aimed to assess the feasibility and performance of the vivid vision perimeter (VVP). The VVP is a piece of software which can be used with off-the-shelf virtual reality (VR) headsets. Recruitment took...

Risk of fractures with glaucoma

In this systematic review and meta-analysis, 7 articles were analysed, with 570,694 subjects and a reported total of 45,957 fractures. The study protocol (CRD42024527785) was registered prospectively. PubMed, EMBASE, and Web of Science were searched from their inception to April...

Low-dose bimatoprost/timolol gel: a new fixed-combination option

This phase III international randomised trial evaluated the efficacy and safety of a new low concentration bimatoprost/timolol eye gel (bimatoprost 0.01%/timolol 0.1%). It was compared with the conventional higher-strength fixed combination eye drops (bimatoprost 0.03%/timolol 0.5%) in patients with open-angle...

Visual acuity improvement in amblyopic eyes following fellow eye vision loss

The authors present a systematic review with the aim of reporting how frequently and to what extent amblyopia recovers following the loss of vision in the fellow eye and identify any potential clinical predictors. Studies including adults with amblyopia and...