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The inflammatory side-effect of Brimonidine
Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...
A novel computerised portable pupillometer detects and quantifies relative afferent pupillary defect
We have all had referrals from A&E telling us that a patient can’t see out of one eye. Sleepily we may ask “Is there an relative afferent pupillary defect (RAPD)?” to evaluate the seriousness of the presentation. The response is...
Prostaglandin-associated periorbitopathy
This is a masked study of 33 patients who had been taking a prostaglandin analogue in one eye only for at least a year, to look for signs of prostaglandin-associated periorbitopathy (PAP). The investigators devised a new grading system to...
Imaging and histological relationship of orbital Schwannomas
This is a retrospective review of 15 patients with orbital Schwannomas comparing the radiological characteristics, in particular the signal intensity on MRI, with the histological sub-types of the tumours. Five patients had MRI imaging alone, three had CT alone and...
Are corneal guttata an additional risk factor in complicated cataract surgery needing a future corneal transplant?
This registry-based cohort study from Sweden utilised data from the Swedish National Cataract Registry and the Swedish Cornea Transplant Registry. Patients who underwent phacoemulsification with a posterior intraocular lens between 2010 and 2012 numbered 192,476. Of these cases, 288 underwent...
Oral glycerol effect on anterior chamber depth during cataract surgery
The authors present the findings of a controlled clinical trial where cataract patients having surgery for both eyes at least seven days apart were given oral glycerol preoperatively when operating on the right eye. This meant that the left eye...
Sensorimotor outcomes following paediatric ocular trauma
A retrospective assessment of sensorimotor outcomes was conducted in paediatric patients after ocular trauma to evaluate potential predictors of poor outcome including time of treatment deprivation, Paediatric Ocular Trauma score (POTS) and patient characteristics. The review was from 2006-2020 and...
Leber’s hereditary optic neuropathy outcomes in an Indian population
A large cohort study in an Indian population is presented, with clinical and genetic profile analysis of patients with Leber’s hereditary optic neuropathy (LHON) treated over a five-year period. The study included 157 patients; 143 male, 14 female (10.2:1 ratio)...
Immunotherapy for orbital SCC
In the UK, cemiplimab is recommended for treating metastatic or locally advanced cutaneous squamous cell carcinoma (SCC) in adults when curative surgery or curative radiotherapy is not suitable. Pembrolizumab is recommended as an option for untreated metastatic or unresectable recurrent...Moorfields International refractive symposium
The Moorfields International refractive symposium covers contemporary vision correction surgery to surgeons in the UK and around the world. Taking place on Thursday 24 April at the Royal College of Physicians in London (08:30 - 17:45), the symposium aims to...Revolutionising eyecare: Gloucestershire’s Community Ophthalmic Link delivers nationally significant results
Ophthalmology is the largest outpatient specialty in the NHS, and in Gloucestershire, it is growing at an annual rate of 2.55%, outpacing other specialties. However, rising demand has led to significant waiting lists, often resulting in patients not being seen...
