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The fragile p-value
Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...
Oral glycerol effect on anterior chamber depth during cataract surgery
The authors present the findings of a controlled clinical trial where cataract patients having surgery for both eyes at least seven days apart were given oral glycerol preoperatively when operating on the right eye. This meant that the left eye...
Fungi in chronic anterior blepharitis
In this prospective, non-randomised cross-sectional study the authors demonstrate the presence of fungi in patients with chronic anterior blepharitis of at least two years duration. Eyelash samples were obtained by epilation with sterile forceps and evaluated with PAS staining, fungal...
Mast cells in Graves’ ophthalmopathy
Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...Blind gaming group levels up at five years
A community of gamers with sight loss from across Scotland and Northern Ireland says its network is thriving as it marks its fifth anniversary. Formed during the pandemic lockdown in November 2020, as part of RNIB’s community work, the group...
Oral proton pump inhibitors in macular degeneration patients
The authors report five patients with advanced wet macular degeneration and poor vision with onset or enhancement of visual hallucinations with the use of proton pump inhibitors for heartburn management. The hallucinations were reversible with discontinuation of medication. The authors...The International Council of Ophthalmology: what is it and is it useful for UK ophthalmologists?
ICO Director for Examinations and Assessments, Simon Keightley, explains the history and role of the organisation today, as well as outlining recent changes to the ICO examinations. The International Council of Ophthalmology (ICO) is the only international medical specialty organisation...
Change in psychosocial, quality of life and anxiety after strabismus surgery
The authors aimed to define the impact of surgical correction on psychiatric problems, health-related quality of life and anxiety levels in children and their parents. This was a cross-sectional study of 39 children with strabismus and their parents. All children...
Causes of abnormal head postures – literature review
Yadegari reports a narrative literature review for abnormal head postures (AHPs) with discussion on different causes. This review summarises the control of a normal head posture before discussing differences of ocular vs non-ocular AHPs. Ocular AHPs may be adopted to...Systemic sarcoidosis presenting with acute myopia and angle closure
Case report A 40-year-old Asian man presented to the Emergency Department with a one day history of sudden onset visual disturbance in his right eye. He complained of image distortion and noted that objects now appeared smaller. He also described...
AI-Based devices in national screening programmes: barriers and challenges
Diabetic retinopathy (DR) may have long-term complications and is recorded as a leading cause of blindness. National DR screening programmes have effectively reduced severe visual loss by timely detection and subsequent treatment of sight-threatening proliferative DR and diabetic macular oedema....
