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Guide to Gaining Approval for a Clinical Study

This article focuses on gaining approval for clinical research involving NHS patients, although the principles can be applied to other types of research. The intention is to give an overview of the requirements for setting up a research study, but...

Clipboard history

If you regularly use the clipboard on a PC or Mac to copy and paste information, you will likely appreciate how useful the feature is. Despite its utility, it fails when you copy data over something else you have yet...

Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

ChatGPT cannot pass FRCOphth examinations: implications for ophthalmology and large language model artificial intelligence

Large language models are generating a lot of hype for artificial intelligence, but can they assist patients and practitioners in ophthalmology? Introduction Deep learning (DL) has emerged in ophthalmology as an exciting form of artificial intelligence (AI) most commonly applied...

Corneal dystrophies simplified

Based on biomicroscopic and histopathologic features, corneal dystrophies can be broadly classified into epithelial, Bowman’s layer / anterior stromal, stromal, and endothelial dystrophies. Corneal dystrophies are a group of inherited, bilateral, gradually progressing, non- inflammatory conditions caused by accumulation of...

Management of diabetic macular oedema in vitrectomised eyes

Diabetic macular oedema (DMO) is one of the leading causes of blindness; its prevalence is on the rise with progressive increase in numbers of people suffering from diabetes. The management of DMO has evolved significantly over the past few years....

Greater awareness of children’s vision care is urged by the profession

Greater attention needs to be given to children’s vision, believes the profession, as a recent survey by Mumsnet reveals that visits to the optometrist are lower down the agenda than dental visits. It found that 9% of parents saw no...

Simplified Ophthalmic Statistics (SOS) Part 1: An introduction to data – how do we classify it and why does it matter?

Introductory statistics courses often start by explaining how data can be classified in different ways. What is not always clear is why you would need to know this. Catey Bunce and Tafadzwa Young-Zvandasara explain. The term data can be applied...

A closed angle seldom comes alone

Case report An 89-year-old lady with dementia was referred to me out of hours by her GP with a few days history of an angry looking left eye for suspected elevated intraocular pressure (IOP). I discovered that this lady first...

Shaping the future: The College of Optometrists holds AI in eyecare summit

On 2 April, The College of Optometrists brought together leading experts, patient and public involvement representatives, policymakers and eye care professionals for its AI in Eye Care Summit. The Summit served as a collaborative platform where key stakeholders discussed and...

Life in the glaucoma laboratory

When people ask me what life in the laboratory is really like, I often pause. On one hand, it is the romantic notion of pushing back the boundaries of science with the daily rhythm of experiments, data and easily obtained...

Survey of parental experience of contact lens support

In this study, the service under evaluation is for paediatric aphakia patients. Soft contact lenses (CLs) are inserted at the time of surgery and remain in-situ for the immediate postoperative period. The aim is for families to undertake daily CLs...