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2025 results found

Bardet Biedl refractive error

This is a retrospective cross-sectional study of 45 patients with genetically diagnosed Bardet Biedl syndrome. Patients with biallelic defects in any gene known to cause Bardet Biedl syndrome were eligible for inclusion. Patients underwent cycloplegic refraction and keratometry. The mean...

The use of virtual reality in paediatric ophthalmology

The purpose of this study was to investigate the utility of virtual reality (VR) in the broader field of paediatric ophthalmology with review of examination, screening, diagnosis, prevention and treatment. This review also explores the potential of eye tracking used...

Associations between cerebral vascular malformations and retinal venous malformations

The authors present a retrospective medical notes review which aimed to understand associations between retinal venous malformations (RVM) and cerebral vascular malformations (CVM). Cases of known CVM over a four-year period were identified. The data extracted from medical records included...

Understanding optic nerve head pericytes and glaucoma

The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

AI glaucoma screening cost-effective in the Netherlands?

Population-wide screening for glaucoma has traditionally been deemed not cost-effective due to high costs and low disease prevalence. This Dutch study re-evaluates this position by introducing artificial intelligence (AI) to the screening model. The authors developed a health-economic model comparing...

My Top Five: Visionary inventions in ophthalmology

When we see how technologically forward and advanced modern-day medicine is, we forget that it is also an age-old, ancient profession with a rich, intriguing history that we remain unaware of. Ophthalmology in particular has always been at the forefront...

Topical cyclosporine A 0.05% for recurrent anterior uveitis

This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...

Comparison of SS-OCT and SD-OCT in polypoidal choroidal vasculopathy

Swept source OCT (SS-OCT) is known to have a longer wavelength than spectral domain OCT (SD-OCT), allowing deeper penetration into retinal and choroidal layers. The aim of this study was to investigate whether SS-OCT is superior to SD-OCT in imaging...

Adjuvant oral voriconazole or oral ketoconazole for fungal keratitis

This randomised double-blinded trial examined clinical outcomes of 50 patients with severe fungal keratitis treated with either adjuvant oral voriconazole or oral ketoconazole. Inclusion criteria were culture or smear proven fungal ulcers >5mm in maximum diameter, involving >4mm of the...

Effect of anti-VEGF treatment on PED morphology

This retrospective study of 30 eyes assessed the effect of anti-VEGF on morphology of pigment epithelial detachments (PED) secondary to age-related macular degeneration (AMD). Thirty eyes of 28 patients with PED were compared to 30 eyes of 30 patients with...

A randomised, controlled trial of oral propranolol in infantile haemangioma

Since its use was first reported in the New England Journal in 2008, propranolol has become the preferred treatment for infantile haemangiomas. However, there is no consensus as to the optimum dose or duration of treatment and there is a...

Comparison of ganglion cell thinning in glaucoma vs. macular hole repair

This prospective study compared the changes in the photopic negative response of the focal macular electroretinogram (fmERG) caused by retinal ganglion cell complex (GCC) thinning at the macula between patients with open angle glaucoma (OAG) and 12 months after successful...