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CRATER 2025

The Conference on Recent Advances in Translational Eye Research 2025

Multimodal Retinal Imaging

Understanding of rapidly advancing retinal imaging techniques is important as they have changed the management of retinal conditions considerably. Interpretation of these tests is a vital skill in the armamentarium of every practising ophthalmologist. The book is directed at general...

OCTA FAZ measurements in vein occlusion

Previous studies have confirmed that foveal avascular zone (FAZ) enlargement is correlated with visual acuity impairment in patients with retinal vein occlusion (RVO). This current study aimed to evaluate the OCT angiography parameters: the area of FAZ, foveal and parafoveal...

Corneal lenticule allotransplant

This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...

Retinal changes in Leber hereditary optic neuropathy

The objective of this study was to describe the changes in the retinal ganglion cell complex (GCC) relative to the retinal nerve fibre layer (RNFL) over time, in patients with Leber’s hereditary optic neuropathy (LHON). For this study, 21 patients...

Central corneal and epithelial thickness measured by Fourier domain OCT

This study examined intraobserver and interobserver reproducibility of corneal thickness (CT) and epithelial thickness (ET) measurement of Fourier domain OCT (RTVue) in 23 healthy volunteers. RTVue is capable of producing 26,000 A scans per second with depth resolution of 5µm....

The prevalence of macular cysts in patients with clinical cone-rod dystrophy determined by spectral domain optical coherence tomography

Cone-rod dystrophy is a progressive photoreceptor disorder which has multiple inheritance patterns. It is rare, with a prevalence of 1 in 40,000. Macular cysts are well recognised in other photoreceptor conditions such as retinitis pigments and choroideraemia, while they are...

Swept source anterior segment OCT

The authors describe a study using the Casia OCT which is a swept source OCT to determine the visibility of the angle structures using two imaging protocols; high density and low density. They randomly selected one eye from 30 normal...

Macular atrophy and choriocapillaris nonperfusion

This Japanese study compared the choriocapillaris (CC) nonperfusion area as measured on OCTA with areas of macular atrophy (MA) measured by fundus autofluoresence (FAF). A total of 44 eyes were assessed (31 were treated with anti-VEGF alone and 13 had...

OCTA to measure surgical haemodynamic changes

This study used the optical coherence tomography angiography (OCTA) technique to evaluate possible haemodynamic changes after horizontal rectus muscle surgery in 32 eyes of 16 patients; nine male, seven female. Recession / resection surgery was undertaken for two horizontal rectus...

OCTA to measure surgical hemodynamic changes

This study used the optical coherence tomography angiography (OCTA) technique to evaluate possible hemodynamic changes after horizontal rectus muscle surgery in 32 eyes of 16 patients; nine male, seven female. Recession / resection surgery was undertaken for two horizontal rectus...

Accuracy of AS-OCT muscle insertion measurements

Anterior segment - optical coherence tomography (AS-OCT) is a non-contact imaging method that can provide accurate measures of extraocular muscles to limbus insertion distances. The authors evaluated the accuracy of AS-OCT for locating horizontal extraocular muscle insertions after strabismus surgery...