You searched for "ophthalmic"

1672 results found

An atypical presentation of Vogt-Koyanagi-Harada Disease

The authors present a single case of atypical presentation of Vogt-Koyanagi-Harada disease. A 42-year-old female presented with unilateral visual loss associated with systemic symptoms of fever and headache. Initial ophthalmic examination revealed a unilateral neuroretinitis, however, investigations for infectious and...

PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

Large collar diameter Jones tubes

This is the first report of the success rates of frosted Jones tubes with larger diameter, 4.5 or 5mm collars. This is a retrospective review of 29 eyes of 25 patients who underwent insertion of a large diameter collar frosted...

Effect of single intravitreal injection of bevacizumab on contrast sensitivity in patients with central retinal vein occlusion

Central retinal vein occlusion is the second most common retinal vascular disorder after diabetic retinopathy. There are many studies reporting the efficacy of intravitreal anti-VEGF injections for macular oedema secondary to retinal vein occlusions. This paper looks at the contrast...

Success rates of primary and revision transcanalicular DCR surgery

Transcanalicular laser DCR is a relatively rare procedure compared to more conventional external or endo-nasal techniques. In this article the authors examine the outcomes of revision surgery following failed transcanalicular diode laser dacryocystorhinostomy (TCDL DCR), comparing a conventional external revision...

Diagnosis and management of orbital vascular malformations

This is an authoritative review of a controversial and difficult clinical area. The authors have experience of over 350 cases and provide a well-structured review of the classification and management of orbital vascular malformations. They emphasise the need to understand...

Analysis and outcome of explanted hydroxyapatite orbital implants

This is a retrospective case series over 11 years of 25 patients with exposed synthetic hydroxyapatite orbital implants who underwent explantation and simultaneous replacement with a dermis fat graft. All patients had signs of infection and had been treated with...

Complement factor B polymorphism and the phenotype of early age-related macular degeneration

The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...

The prevalence of macular cysts in patients with clinical cone-rod dystrophy determined by spectral domain optical coherence tomography

Cone-rod dystrophy is a progressive photoreceptor disorder which has multiple inheritance patterns. It is rare, with a prevalence of 1 in 40,000. Macular cysts are well recognised in other photoreceptor conditions such as retinitis pigments and choroideraemia, while they are...

Extraocular muscle BT after ocular pathology

Management is described for 13 patients who received inferior rectus botulinum toxin (BT) injection for vertical strabismus due to orbital pathology. Patients were aged 19-86 years, eight were female and seven were right eye injections. Orbital pathology included six with...

Diabetic retinopathy and body fat distribution and adipokine secretion in type 2 diabetics

The major risk factors for diabetic retinopathy (DR) in patients with diabetes are poor glycaemic or blood pressure control, duration of diabetes and nephropathy related to the severity of DR. Several studies suggest that DR is associated with visceral fat...

Complement Factor H and Factor H-Like protein are expressed in human RPE cells

The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...