You searched for "research"

2249 results found

Long-term treatment for diabetic macular oedema

The authors set out to characterise anti-VEGF treatment patterns and long-term outcomes in patients with diabetic macular oedema. A retrospective analysis of over 190 thousand patients on the Intelligent Research in Sight registry was performed. Of these, 1236 eyes have...

How the thinking machine is transforming the retinal landscape

Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...

Smartphone use in adolescents and association with ocular symptoms and binocular issues

In this study, the proportion of ocular symptoms and binocular dysfunction was evaluated to determine their association with smartphone use on adolescents aged 10–19 years. This was a cross-sectional study of 123 participants (52% male, 48% female) with a mean...

How does teprotumumab impact on ocular misalignment in thyroid eye disease?

A retrospective case review was conducted with the aim of exploring the effect of teprotumumab on objective diplopia. Adults diagnosed with thyroid eye disease, presenting with diplopia and receiving a standard six-month treatment with teprotumumab at a single centre were...

Developing a data registry for neuro-ophthalmology with quality assurance measures

The authors aimed to report the scope of neuro-ophthalmology clinics in Australia, referral patterns and develop a quality assurance framework for referrals. Cases were identified from a single tertiary neuro-ophthalmology centre. Data was prospectively collected into the National Neuro-ophthalmology Database...

Strabismus prevalence in a Pakistan population

The aim of this study was to compile the available literature reporting the prevalence of strabismus in Pakistan and calculate the pooled prevalence of strabismus in the Pakistan population. Meta analysis was conducted with 10 studies with a total of...

In conversation with Robert MacLaren

Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...

Pioneering eye device restores reading vision to blind eyes

A pivotal European clinical trial of a new electronic eye implant has seen remarkable results. The study, published in the New England Journal of Medicine, showed 84% of participants were able to read letters, numbers and words using prosthetic vision...

Understanding the pachychoroid disease spectrum

This article provides a comprehensive review of the pachychoroid disease spectrum, a group of chorioretinal disorders characterised by abnormal choroidal thickening and various pathological changes in the choroid, retinal pigment epithelium, and retina. It also highlights the controversies and knowledge...

QuickSee Free autorefractor results in outreach settings

The Gambia screening project was launched in 2022 to provide vision screening for school-aged children. Within this screening programme, the refractive error measurements of the QuickSee Free autorefractor were compared to cycloplegic refraction in this outreach setting. Six rural schools...

Understanding optic nerve head pericytes and glaucoma

The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

Retinal thickness and visual acuity change correlations after amblyopia occlusion therapy

This prospective study aimed to assess change in retinal nerve fibre layer (RNFL) and macular thickness, and clinical correlations with visual outcomes, after amblyopia treatment in 30 children with moderate to severe amblyopia. Mean age of children was 5.26 ±1.65...