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Ginko bilboa extract affects hypoxic retinal pigment epithelial cells
Wet age-related macular degeneration (AMD) is characterised by choroidal neovascular membrane (CNVM) formation. It is thought that localised hypoxia within the retina results in overexpression of growth factors such as vascular endothelial growth factor (VEGF), which induces CNVM formation. VEGF...
Mono vs. multi-therapy in IOP control
This randomised control trial studied newly diagnosed glaucoma patients given mono‐ or multi‐therapy regarding differences in initial intraocular pressure (IOP) reduction, target IOP levels reached and influence of untreated baseline IOP on IOP reduction. Patients newly diagnosed with manifest primary...
Contrast sensitivity after laser corneal surgery
This study group compared contrast sensitivity among participants undergoing wavefront-guided or wavefront-optimised photorefractive keratectomy (PRK) or laser-assisted in situ keratomileusis (LASIK) for the treatment of myopia or myopic astigmatism 12 months after surgery. This was a prospective, randomised clinical trial,...
IVTA for diabetic macular edema and macular edema secondary to retinal vein occlusion: a meta-analysis
This meta-analysis aimed to compare the safety and efficacy of different doses of intravitreal triamcinolone acetonide (IVTA) for diabetic macular oedema (DME) and macular oedema (ME) secondary to retinal vein occlusion (RVO). A systematic literature search for randomised controlled trials...
Type 3 macular neovascularisation (MNV) due to age-related macular degeneration
This paper systematically reviews and summarises the current knowledge on type 3 neovascularisation due to age-related macular degeneration which is defined as neovascularisation originating from the retinal deep capillary plexus that grows towards the outer retina often penetrating the level...
Verteporfin shortage: treatment options and outcomes in chronic non-resolving central serous chorioretinopathy
Half-dose photodynamic therapy (HD-PDT) with verteporfin has been the therapy of choice in non-resolving central serous chorioretinopathy lasting longer than four months. Since 2021, a worldwide shortage of verteporfin due to manufacturing issues prompted adjustments in treatment practices. This retrospective,...Ambitions for sustainable service recovery amidst an escalating post-COVID backlog
Rod McNeil reviews plans, activity and solutions to better address the post-COVID backlog and bolster sustainable service recovery. Ophthalmology was the busiest outpatient specialty during the three years to March 2020 across the English NHS and again recorded the highest...New solutions in the prevention and treatment of Acanthamoeba keratitis
The global increase in Acanthamoeba keratitis infections has emphasised the inefficiencies of current treatment and preventative methods, here researchers from the West of Scotland detail a promising new series of compounds that may stem the tide. News headlines detailing horror...VISION 2020 LINKS Programme: Reviewing the first ten years and announcing the new diabetic retinopathy initiative
The VISION 2020 LINKS Programme celebrates its 10th anniversary next month. Over the past decade it has achieved its objective of building capacity for eye care in developing countries, particularly in Africa, by establishing long-term training partnerships between institutions, known...Management of diabetic macular oedema in vitrectomised eyes
Diabetic macular oedema (DMO) is one of the leading causes of blindness; its prevalence is on the rise with progressive increase in numbers of people suffering from diabetes. The management of DMO has evolved significantly over the past few years....
