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A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention

To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....

Prognostic factors for visual acuity in patients with LHON after gene therapy

This retrospective study investigates prognostic factors affecting the visual acuity after a single intravitreal injection of rAAV2-ND4 gene therapy in 53 patients with Leber’s hereditary optic neuropathy (LHON) with mutation at site 11 778. Patients were reviewed one and three...

Confocal microscopy and corneal graft rejection

Forty-five patients following penetrating keratoplasty (PK) were examined with the HRT III Rostock Cornea Module confocal microscope at various points after their surgery for two years. Activated keratocytes (AKs) were counted manually and their mean number evaluated. A pattern was...

Revision of orbital fracture repairs

This is a retrospective review of 13 patients with sub-optimal outcomes following primary orbital fracture repairs who underwent revision surgery. All had fractures of the orbital floor, with four involving other orbital walls, and six also involving other facial bones....

Keratoconus: Diagnosis and Management

From the history of keratoconus to its diagnosis and management, this book covers everything. Don’t be fooled by thinking keratoconus is a simple disease like I did; this book is dense, and packed with information. The book is divided into...

An Inconvenient Truth: Pete’s hidden curriculum Part 4

“What gets us into trouble is not what we don’t know. It’s what we know for sure that just ain’t so.” The above is a quote attributed to Mark Twain from the 2006 documentary, An Inconvenient Truth, which follows Al...

Inverted internal limiting membrane flap vs internal limiting membrane insertion technique for large macular holes

This meta-analysis aimed to compare and evaluate the morphological and functional outcomes between the inverted internal limiting membrane (ILM) flap and ILM insertion techniques in the treatment of large macular holes (MHs). The primary outcome measures were defined by the...

Nominations open for AOP elected and designated Council positions

The Association of Optometrists invites nominations from eligible members for its 2024 Council elections.

OPO celebration event marks 100-years of groundbreaking research in vision science and optometry

The College of Optometrists hosted academics from across the UK and internationally at a special symposium to mark 100-years of its research journal Ophthalmic and Physiological Optics (OPO) at Glasgow Caledonian University. OPO Centenary: Celebrating Research Excellence saw academics and...

Implications of missed foreign bodies under the upper eyelid

Children aren’t the best historians. As a result, clinicians sometimes rely on the accounts of parents regarding problems. Missed foreign bodies due to poor histories or incomplete examinations may result in irreversible loss of vision. This case report shines light...

It’s All in Your Head: Stories from the Frontline of Psychosomatic Illness

Have you ever reviewed a patient with unexplained symptoms? It’s All in Your Head by Consultant Neurologist Dr Suzanne O’Sullivan is a non-fiction book about patients with psychosomatic disorders. In each of the nine book chapters, she presents an anonymised...

Patients blinded by stem cells! How safe are they really?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Patients blinded by stem cells! How safe are they really? Ever since the successful results following...