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Cytokine levels in vitreous fluid in patients with pathological myopia

Pathological myopia (PM) is a leading cause of irreversible visual impairment worldwide, and efforts are dedicated to the study of its underlying mechanisms. Axial extension of the eyeball is regulated via a cascade of biochemical molecules that are initiated in...

Shocking experiences of blind patients lead to improved cervical screening standards

Blind women in Scotland have reported distressing experiences when attending cervical screening appointments, with some describing procedures as “rough” and “painful,” and feeling uninformed and unsupported throughout. There are over 180,000 people with sight loss in Scotland, of whom 60%...

The last three patients: general practice (Patient One)

Professor Jonathan Rees is an Emeritus Professor of Dermatology at the University of Edinburgh (2020). He held the Grant Chair of Dermatology in Edinburgh from 2000 to 2020, and before that the Chair of Dermatology in Newcastle from 1992 to...

Development of eyecare services in Dominica: Past, present, and future

Dominica is a small island developing state in the Caribbean with a population of approximately 73,000 people [1] and has a long and proud history of developing eyecare services through international partnerships. This article will give you an outline of...

Informed consent in ophthalmology care in the UK: A critical component of patient‑centred practice

Informed consent is a cornerstone of ethical and legal practice in healthcare, particularly in fields like ophthalmology where specialised interventions can have significant implications for a patient’s vision and quality of life. In the UK, informed consent is not merely...

Central corneal and epithelial thickness measured by Fourier domain OCT

This study examined intraobserver and interobserver reproducibility of corneal thickness (CT) and epithelial thickness (ET) measurement of Fourier domain OCT (RTVue) in 23 healthy volunteers. RTVue is capable of producing 26,000 A scans per second with depth resolution of 5µm....

Chronic drop use and trabeculectomy on tear osmolarity

Ocular surface disease (OSD) is common in patients chronically treated for glaucoma. This may be related to the drug itself but often to the preservatives in the medication. Much work has been done on the most common preservative, benzalkonium chloride...

Tear production levels and dry eye disease

Dry eye disease (DED) is multifactorial, caused by an alteration in the quality or quantity of tear film’s three layers. Several tests are available for diagnosis. The aim of this study was to determine if the Schirmer test (ST) could...

Visual outcome and surgical results in children with Marfan Syndrome

Eighty-two eyes of 41 patients with a genetically proven diagnosis of Marfan syndrome were retrospectively analysed. Twenty-seven had bilateral subluxation and 14 received lensectomy. Follow-up was three years. Mean visual acuity (VA) was 0.1 ±0.7 logMAR in patients with normal...

Real world results of cataract surgery in pseudoexfoliation

In this single-centre retrospective cohort study, the data of pseudoexfoliation (PXF) patients undergoing phacoemulsification cataract surgery from January 2010 to December 2019 was analysed in the National Health Service setting. The study comprised 23,329 eyes of 15,257 patients. Patients with...

Endothelial keratoplasty (EK) with anterior chamber intraocular lens (ACIOL) versus secondary posterior chamber lens (PCIOL)

This is a retrospective study of 82 eyes (23 ACIOL, 59 PCIOL) with a history of either pseudophakic (PBK) or aphakic (ABK) bullous keratopathy, who had descemet stripping automated endothelial keratoplasty (DSAEK) with retained or secondary ACIOL, or DSAEK with...

Optoversity Challenge draws 12 universities together

Out of the Box Optic’s Optoversity Challenge 2025 has brought 95 students from 12 UK universities together to take part in the exciting competition. The annual event – now in its ninth year – is a major fundraiser for Vision...