You searched for "Retina"
The next wave of AI in ophthalmology: From screening to communication
Artificial intelligence (AI) is reshaping ophthalmology, moving from research laboratories into everyday clinical care [1]. With its strong reliance on imaging and pattern recognition, ophthalmology is uniquely positioned to benefit from AI innovations. These developments range from autonomous disease screening...My Top Five: Emerging robotic and automated innovations in ophthalmological surgery
Robotic technology is redefining the landscape of ophthalmological surgery by enabling micron-level precision and control beyond human capability. Intraocular microsurgery remains challenging to perform, with concerns about accuracy, tremor, precision, depth perception and dexterity. Moreover, conventional surgical tools have only...Ophthalmology specialty training applications: a costly affair?
Ophthalmology is one of the most competitive specialties to pursue training in worldwide. In the United Kingdom, the ST1 entry national selection competition ratio for the past few years has ranged between four to five applicants per post [1]. The...Are we short-sighted about myopia?
Worldwide prevalence of myopia has increased rapidly in recent years and has now reached epidemic levels, particularly in South-East Asia where prevalence is around 80% [1-4]. Myopia prevalence is also increasing in the United States and Europe where it is...
Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
Myopic choroidal neovascularisation
This is a review article summarising the latest myopic CNV (choroidal neovascularisation) literature in the clinical experience and management outcomes for recommendation algorithm. The aetiology of the myopic CNV was discussed by the authors under the heading of the heredo-degenerative...
Are retinal vein occlusions seasonal? And if so why might that be?
Some studies have reported a strong seasonal pattern to central retinal vein occlusion (CRVO) occurrence with a peak in January, but other studies have failed to replicate this finding. The authors sought to determine data for Stockholm’s seasonal variation in...
Intravitreal dexamethasone implant for diabetic macular oedema
The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...
Ranibizumab versus laser in diabetic macular oedema (LUCIDATE study)
The aim of this study was to compare the functional and structural effects of Ranibizumab versus macular laser treatment in patients with diabetic macular oedema. It was a single centre, prospective, randomised, single masked clinical trial spanning a 48 week...
Effect of change in retinal nerve fibre layer thickness on quality of life in patients with glaucoma
The authors investigated the relationship between structural changes in glaucoma (retinal nerve fibre layer (RNFL) thickness) and quality of life (as measured by the NEI VFQ-25 questionnaire) over a period of time. Two hundred and sixty eyes of 130 patients...
Long-term effect of gene therapy on Leber’s congenital amaurosis
After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...
