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Shedding light on Wolfram syndrome: The unveiling of a delayed diagnosis

12 August 2025 | | EYE - Neuro-ophthalmology
Wolfram syndrome 1 (WS1) was first described by Wolfram and Wagener in 1938 and it’s a rare neurodegenerative, progressive disorder, also known as DIDMOAD (diabetes insipidus, diabetes mellitus, optic atrophy, and deafness) [1]. We present an atypical case of WS...

Help the VISION 2020 LINKS & Networks Programme to save children’s sight and lives

3 October 2024 | | EYE - Vitreo-Retinal
The LINKS & Networks Programme was established at the International Centre for Eye Health (ICEH), London School of Health and Tropical Medicine (LSHTM), 20 years ago to improve the quality and quantity of eye health services in low- and middle-income...

Human factors in the operating room

3 June 2021 | | EYE - Cataract, EYE - Refractive, EYE - General
The importance of minimising human error in surgery is well established. This was initially sparked by lessons learned from the aviation industry in the 1970s after several fatal flight accidents [1]. This became a catalyst for a movement on training...

“Herr Doktor, I can’t see but I am driving”

1 February 2018 | | EYE - Vitreo-Retinal, EYE - General
This 56-year-old lady was quite puzzling. With her own glasses and the pinhole she merely managed to see the 1.3 and 1.0 logMAR lines with her right and left eye, respectively (I am currently working in Germany again, so goodbye...

A log in the eye

1 February 2017 | | EYE - Vitreo-Retinal
"My friend wanted to show how far he could throw that log. So, he helicoptered it over his head, faster and faster and when he let go, it hit my eye at full speed,” a young lady of 19 years...

Under pressure: a tool to aid the 
non-ophthalmic practitioner in the timely management of acute angle closure

1 April 2017 | | EYE - Glaucoma, EYE - Neuro-ophthalmology
Acute angle closure is a true ophthalmic emergency that mandates timely diagnosis and treatment. The priority in initial management is to lower the intraocular pressure in an expeditious matter using medical treatments. The risk of irreversible glaucomatous optic neuropathy is...

What you learn after performing 10,000 cataracts

1 May 2018 | | EYE - Cataract, EYE - Refractive
What do you do when the anterior chamber shallows, or the zonules give way? How do you handle the stubborn epinuclear plate? Raymond Radford shares the benefit of his experience when dealing with tricky cataract surgery. Firstly, you realise you...

What to expect when meeting a statistician

1 August 2014 | | EYE - General
There are a growing number of statisticians working closely with ophthalmologists. They have different training but they are driven by the same goal: to perform high quality evidence based clinical research [1,2]. In a perfect world we would simply conduct...

Thinking outside the box – adapting to the COVID-19 lockdown

5 August 2020 | | EYE - Glaucoma, EYE - General
How can we avoid further delays to follow-up in glaucoma patients? The author asks if there is a socially distanced way to check IOPs in those at high risk of losing vision. Glaucoma is an asymptomatic condition. Loss of the...

Navigating the retina: the nitty-gritty of slit-lamp fundus examination

3 August 2023 | | EYE - Vitreo-Retinal
The slit-lamp fundus examination can be a difficult and disorientating task for beginners due to the retina being viewed in a non-anatomical orientation, the small area of retina illuminated, and the counterintuitive technique of the examination. This article provides a...

Running a high-volume nurse led intravitreal service using the Sp.eye device – the Stanley Eye Unit experience

2 February 2024 | | EYE - Vitreo-Retinal
Introduction The vast majority of ophthalmology units utilise allied healthcare professionals (AHPs) to deliver intravitreal injections (IVIs). The Royal College of Ophthalmologists issued a statement 10 years ago advocating the use of non-medical practitioners performing IVIs [1]. The main benefit...

My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...