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1301 results found

Effect of intra-arterial chemotherapy drug regimens on globe salvage outcomes of retinoblastoma patients

This is a retrospective study from Shandong University, China, between May 2016 to November 2019, to compare the effect of 3-drug regimen (melphalan (MP) , topotecan (TP) and Carboplatin (CP)) of 95 patients (97 eyes) with two-drug regimen (MP and...

Use of immunomodulatory treatment for non-infectious uveitis: an International

Two-hundred-and-twenty-one group members from 53 countries completed a questionnaire on their indications, investigations and use of conventional and biologics and follow-up of treated patients. Main indications to start systemic immunomodulatory drugs were: uveitis not controlled by oral prednisolone (94.1%), specific...

Three-year results of 0.01% and 0.1% loading dose atropine treatment including washout in Danish children with myopia: a placebo-controlled, randomised clinical trial

This was a placebo-controlled, double-blind, randomised clinical trial of 97 children to examine the safety and efficacy of low-dose atropine (0.1% and 0.01% loading dose) after 2-year treatment and 1-year washout in 6–12-year-old Danish children with myopia. Ninety-one children were...

Prism fusional vergence measures for Risley vs prism bar measurements

This study sought to investigate the agreement between the phoropter Risley and the prism bar prism fusional vergence amplitudes among a normal sample of Ghanaian children aged 8–17 years. This was a school-based study of 2300 children. Of 2300, 116...

Choice and definitions of surgical outcomes for intermittent exotropia

This review was conducted to address a number of questions: (1) define successful surgical outcome; (2) criteria for successful alignment, (3) consideration of aetiology when deciding surgery, and (4) are visual acuity, fusion and stereoacuity routinely investigated as surgical outcomes?...

Diagnostic yield of routine metastatic work-up in conjunctival melanoma

Conjunctival melanoma (CM) is a rare but potentially aggressive malignancy of the ocular surface with high rates of local recurrence and metastasis. Eighty-one consecutive patients with invasive conjunctival melanoma treated by the senior author over the course of 23 years...

OSA dry eye disease group forms for technology providers

Dry eye disease diagnostic and therapy technology providers have formed a specialist OSA and Optic UK group to collaborate and provide optimum support for the profession. Led by Ross Bailey, SCOPE Eyecare Professional Relations and Partnerships Manager, and Nicola Bennett,...

Investigation of PAX7 positive satellite cells in extraocular muscle surgery

PAX7 is a transcription factor and is expressed in non-active and activated satellite cells. It is needed for muscle progenitor function, survival and expansion. This study investigates the effect of recession/resection surgery on PAX7-positive satellite cells in extraocular muscles of...

Eye Emergency Study Day for Doctors

Join us for a dynamic, hands-on study day designed to strengthen your confidence and skills when dealing with ophthalmic emergencies. This interactive day combines theoretical learning working through clinical scenarios, ensuring you leave equipped to oversee the initial management of...

What's trending Oct/Nov 2019

#probeyeotic #eyeballbugs #microbiome The human microbiome usually conjures up images of the gastrointestinal tract and yoghurt containing good bacteria. However, research suggests that the ocular mucosa is home to a unique microbe collection, with important immunological functional properties [1]. This...

The power of the full blood count

Vishal Shah walks us through his thought process whilst highlighting the importance of routine investigations when dealing with unusual retinovascular presentations. Retinal changes can arise in anaemia, leukaemia, lymphoma, myeloproliferative and myelodysplastic syndrome. They are often the first manifestation of...

Crystalline keratopathy in monoclonal gammopathy of undetermined significance

Monoclonal gammopathies encompass a group of plasma cell disorders characterised by the excessive production of abnormal monoclonal immunoglobulins in the bloodstream [1]. This category includes multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), amyloidosis and other lymphoproliferative disorders. Monoclonal gammopathy...