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Conjunctival inflammation in glaucoma patients
Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...
Glaucoma surgery in Sturge-Weber syndrome
The authors report the largest retrospective study of surgical results of goniotomoy and trabeculectomy for 42 patients (46 eyes) with glaucoma associated with Sturge-Weber syndrome (SWS). There were 18 males and 24 females, and 62 goniotomy procedures (51 goniotomy surgery,...
Possible mechanism for infant development of secondary glaucoma
The authors consider published evidence with regard to potential causative mechanisms for secondary glaucoma that follows infant lensectomy. They review clinical and laboratory studies. The mechanism they propose is that the original lensectomy surgery releases immature anterior lens cells into...
ROPScore for detection of any and severe ROP
ROPScore is a free tool consisting of a logistic regression equation to calculate the risk per child and calculated one time per infant at six weeks of life. It helps to predict severe retinopathy of prematurity (ROP). This study aimed...
BESTi: a new index to detect subclinical keratoconus
In this multicentre, case-control study, the authors develop a new index, named Boosted Ectasia Susceptibility Tomography Index (BESTi), to detect early cases of keratoconus. This index was derived from multiple logistic regression analysis of 22 variables of tomography scans. The...Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...It’s not always GCA
Giant cell arteritis (GCA) is an immune mediated granulomatous inflammatory disease that affects muscular middle or large sized arteries. It is considered as a continuation of polymyalgia rheumatica (PMR) when the severity of the disease has increased. It is the...My Top Five: Tips for maximising your ophthalmology elective in the UK as an international medical student
Practical strategies for international medical students to maximise their ophthalmology elective in the UK, including networking, skill building and research opportunities. An ophthalmology elective is an incredible opportunity to gain hands-on experience, develop clinical skills and connect with professionals in...Exploiting nature’s randomised trials of eye disease
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...The value of hospital placements in ophthalmology in general practice specialty training
Pratik Bikkannavar provides insights into the potential benefits a placement in ophthalmology provides General Practice Specialty Trainees (GPSTs) and its valuable purpose for the wider ophthalmic community. Ophthalmic complaints are known to account for up to 1 in every 20...The VISION 2020 LINKS Programme: Cascading leadership training in Calabar, Nigeria
The VISION 2020 LINKS Programme has initiated ‘LEAD FORWARD’, an innovative leadership development project incorporating a commitment to cascade training and participate in achievable quality or service improvement projects. The project provides opportunities to apply leadership skills in practice as...
