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General purpose AI: Transitioning from high performance in highly curated settings to useful applications in ophthalmology
Artificial intelligence (AI) may be understood as the ability of machines to perform tasks which otherwise require human perception, reasoning, or learning. With the advent of deep learning, AI has achieved remarkable results across a wide range of medical tasks...Ophthalmology in the developing world
After the second year of medical school, I spent my summer vacation working as a volunteer for a small Italian non-government organisation (NGO), named HEALTH-AID. As part of my volunteering experience, I joined a team of European doctors, medical students...
Outcomes of reinjection of Ranibizumab for reactivation of retinopathy of prematurity
The authors present their data from Egypt assessing the effects of Ranibizumab reinjection for neonates with retinopathy of prematurity (ROP). Doses given were 0.25mg/0.025mL. They screened 2318 infants with 115 (5%) of infants with a mean post menstrual age (PMA)...
Is pre-eclampsia / eclampsia a risk factor for non-infective uveitis?
This population based retrospective matched cohort study was the first of its kind to suggest an association between preeclampsia / eclampsia (PEE) and non-infective uveitis (NIU). They used the Longitudinal National Health Insurance database in Taiwan to assess 2073 post-delivery...
Tutopatch® in surgical management of third nerve palsy
his study evaluates the benefit of using Tutopatch® to elongate the extraocular muscles in patients with third nerve palsy who have residual strabismus after unsuccessful surgery and no other surgical options considered to be appropriate. The study included nine patients...
γδ T cell depletion does not affect fungal keratitis
Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...
Sirolimus for lymphatic-venous malformation
This is a case report on the use of oral sirolimus in the treatment of lymphatic-venous malformations. This condition can often be sight-threatening when present in the orbit and traditional management options have included observation, sclerotherapy and surgery. Both sclerotherapy...The role of inflammation in the pathophysiology of DMO
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...
Clinical features of basic acquired nonaccommodative esotropia requiring surgery
Basic acquired nonaccommodative esotropia (BANAET) is a concomitant esotropia occurring after the age of six months without significant refractive error or accommodative element. Esotropia is similar for both near and distance and children have prior binocular single vision. The purpose...The College of Optometrists responds to the abolishment of NHS England
Dr Gillian Rudduck MCOptom, President of The College of Optometrists, commented: “The announcement today of the scrapping of NHS England must not slow the progress of reform and the government’s plans to shift focus from hospitals to primary care. With...
Wide variation in the volume of the sphenoid trigone
This is a radiological study of the volume of the sphenoid trigone in normal subjects. The authors were interested to see how much volume could be gained by removal of the trigone during an orbital decompression for thyroid eye disease....
