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Positives and negatives of managing diplopia in adults with prisms

This study recruited consecutive patients prescribed prisms during a two-year period, within set criteria of a deviation up to 30 prism diopters, good fusion, willingness to wear prisms and no previous unsuccessful use of prisms. The majority of cases had...

The interpretation and use of ultrasound biomicroscopy (part 1)

Ultrasound Biomicroscopy (UBM) has become increasingly important for the diagnosis of a variety of anterior segment pathologies. Most ophthalmologists are familiar with conventional B-scan ultrasonography techniques, which operate at lower sound frequencies (7.5 to 20MHz). UBM is an ultrasound technique...

Lost in translation

The article that follows is a collection of reflections and observations by Peter (British) and Nathan (Singaporean) living and working in each other’s countries. Peter Cackett “Best thing about this place is it’s not still full of pompous ex-colonials who...

Volunteer abroad: the Khmer Sight Foundation

A team of volunteers describe their experiences of working with the Khmer Sight Foundation in Cambodia. Cambodia has a population of 15 million people, of whom an estimated 300,000 are blind. This figure is increasing by 10,000 each year. Three-quarters...

Complement factor B polymorphism and the phenotype of early age-related macular degeneration

The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...

Aflibercept treatment in polypoidal choroidal vasculopathy

The authors present a study to evaluate the anatomical and functional efficacy of aflibercept intravitreal (IVT) as a monotherapy in polypoidal choroidal vasculopathy (PCV) in a Caucasian population treated with initial three-monthly aflibercept IVT, followed by a bimonthly regimen for...

Adjuvant intravitreal dexamethasone implant for persistent CME

In this retrospective, cross-sectional study the authors investigate the efficiency of intravitreal dexamethasone implants (0.7mg) for cystoid macular oedema (CME) persisting, despite immunomodulatory treatment in patients with Behcets’ disease (BD). Twenty-seven eyes of 20 patients (12 males and eight females)...

VIBIM Study: One-year results of treatment of DME with aflibercept using TnE

The VIBIM study (the treat-and-extend regimen (TER) using intravitreal aflibercept in diabetic macular edema (DME) study) was designed to evaluate the efficacy of the TER using aflibercept in the management of DME for a period of two years. The authors...

Ocular hypertension following intravitreal steroid injections: a comparative study between triamcinolone-acetonide and dexamethasone-implant

This was a retrospective observational study of steroid response following 1549 intravitreal steroid (TA and Dex) injections. One thousand and seventy-five eyes of 897 patients were reviewed. Glaucoma patients, glaucoma suspects, uveitis, trauma, and cases with less than one month...

Ocular manifestations of Whipple’s disease

In this retrospective review of 217 patients with Whipple’s disease (WD), the authors reviewed the presentations of those with ocular manifestations. Ocular signs of WD are under recognised, frequently resulting in misdiagnosis and mismanagement. Mayo Data Explorer, a Mayo Clinic...

Narrative literature review for intermittent exotropia

This is a narrative literature review on prevalence, terminology, risk factors, natural history and clinical characteristics for intermittent exotropia. A Medline search was conducted with no date restrictions up to September 2020 and collating English language studies. Prevalence was reported...

Consultations for ‘papilledema’ for inpatients and in the emergency department

This study aimed to establish the final diagnosis and outcomes for neuro-ophthalmology emergency department (ED) and inpatient consultations for ‘papilledema’. Neuro-ophthalmology consults from ED and inpatient wards for adults referred with ‘papilledema’ were prospectively collected for 12-months in a single...