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Ethnic disparities in diagnostic sequencing yield

The authors present a systematic review and meta-analysis of the diagnostic yield of next generation sequencing (NGS) for inherited retinal diseases and compare yield from studies performed primarily on patients of European descent from those primarily of East Asian descent....

Diagnostic yield of routine metastatic work-up in conjunctival melanoma

Conjunctival melanoma (CM) is a rare but potentially aggressive malignancy of the ocular surface with high rates of local recurrence and metastasis. Eighty-one consecutive patients with invasive conjunctival melanoma treated by the senior author over the course of 23 years...

Ultra-widefield fundus autofluorescence

The authors assessed the ease and utility of ultra-widefield fundus autofluorescence (UWF-FAF) in detecting suspected inherited retinal disease in children who were difficult to examine. They aimed to assess the sensitivity of UWF-FAF and UWF-CF (colour fundus) photography and clinical...

Progression in the Early Manifest Glaucoma Trial

The Early Manifest Glaucoma Trial (EMGT) had previously demonstrated without doubt that intraocular pressure reduction decreased the risk of progression in patients with early glaucoma. In this analysis of 306 eyes over eight years from the EMGT, perimetric and optic...

Visual outcomes, visual fields and optical coherence tomography in paediatric craniopharyngioma

This study reviews the visual outcomes of ten patients under the age of 18 years with craniopharyngioma. The paper also reviews the correlation between visual field (VF) testing and optical coherence tomography (OCT) examination and evaluates the role of OCT...

Avoiding prominent facial features during perimetry

The authors present a case series including six healthy participants prospectively recruited. All participants had no ocular pathology. The assessment included identification of their dominant eye for use in testing. A 60-4 SITA standard visual field assessment was completed in...

Unexplained vision loss following exposure to combat

Non-organic vision loss (NOVL) is defined as a decrease in visual acuity or visual field without an identifiable organic cause. NOVL can be particularly challenging and time-consuming to diagnose, especially where the vision loss is superimposed on an element of...