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1854 results found

ARN in North Africa

1 December 2015 | | EYE - Vitreo-Retinal
Acute retinal necrosis (ARN) is a rare cause of uveitis. This paper aims to outline the clinical features of 12 patients with ARN in a referral centre in Tunisia, North Africa. A retrospective review of case notes was carried out....

CD40L activation of human RPE cells

1 August 2018 | | EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...

Sutureless 27-gauge needle intrascleral intraocular lens implantation

1 June 2014 | | EYE - General
The authors report on a prospective, non-comparative, interventional case series of patients undergoing sutureless intrascleral fixation of a posterior chamber three piece intraocular lens (IOL) using a 27-gauge needle for docking. Sutureless techniques have the advantage of not having complex...

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

1 October 2019 | | EYE - Vitreo-Retinal
Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...

Use of pattern-reversal VEP in congenital Zika syndrome (CZS) assessment

1 February 2022 | | EYE - Paediatrics, EYE - Strabismus
The authors conducted pattern reversal visual evoked potential (PRVEP) in children with congenital Zika syndrome (CZS) and report the correlates with visual acuity, fundus alterations and severity of microcephaly at birth. This was a cross-sectional study of 37 children with...

ISD-DE (International Society of Dacryology and Dry Eye) Meeting 2024

29 May 2024 -31 May 2024
by Jane Olver, FRCS FRCOphth, President ISD-DE and 2024 London Meeting Organiser, owner and Medical Director, Consultant Oculoplastic Surgeon, Clinica London. The International Society of Dacryology and Dry Eye (ISD-DE) 2024 update course and scientific meeting ran between 29, 30...

A single intravitreal bevacizumab in the treatment of breast carcinoma related choroidal metastasis

1 June 2015 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Case report Choroidal metastasis represents a common form of intraocular malignancies occurring in up to 10% of patients with systemic metastasis [1]. The most common primary sites of ocular metastasis are breast carcinoma in women and lung carcinoma in men,...

Global health and conflict: the unseen consequences

27 October 2021 | | EYE - Orbit, EYE - General
Global eye health inequalities stem from poor access to affordable care, causing preventative vision impairment and blindness. In 2020, a study showed that 510 million people, the majority being in low-income and middle-income countries, had uncorrected near vision impairment simply...

Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation

4 December 2023 | | EYE - Neuro-ophthalmology
An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...

In conversation with Andrena McElvanney (President, MCLOSA)

22 September 2022 | EYE - Cornea
We spoke to Andrena about MCLOSA's annual meeting this November, key developments in cornea and external eye disease, and plans for the association’s 30th anniversary. Andrena McElvanney (top, second from right) and the OSI council members. The Medical Contact Lens...

Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management

1 December 2016 | | EYE - Vitreo-Retinal
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...

Birdshot retinochoroiditis

1 June 2022 | | EYE - Vitreo-Retinal, EYE - General
Birdshot retinochoroiditis (BRC) is a chronic, sight-threatening uveitis, most commonly affecting caucasian individuals in their fourth to sixth decades [1]. The disease is associated with HLA-29 and is characterised by progressive inflammation at the level of retina and choroid, with...