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RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions
This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...
Repeated orbital decompression surgery
This is a retrospective review of nine redo orbital decompressions in six patients. All operations were performed for dysthyroid optic neuropathy, both initially and when repeated. The interval between first and redo decompressions varied from one to 15 years and...
Change in infantile exotropia
This study investigated the clinical course of patients with infantile exotropia who initially presented with a small exo deviation of 10-18 prism dioptres. Eighty-six patients were reviewed: 35 with follow-up of >2 years without surgery and 51 with surgery. The...
Genetic analysis of choroideremia families
Choroideremia (CHM) is a rare X linked recessive chorioretinal dystrophy. Symptoms include nyctalopia and progressive peripheral field loss. Female carriers may have mild symptoms. Choroideremia is known to be caused by a mutation in the CHM gene. A multicentre human...
Differential inhibition of EAU by CTLA4 and IL-6
Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...
Could medical cannabis be used to successfully treat blepharospam?
This study observed the effect of medical cannabis in benign essential blepharospasm (BEB), in addition to standard botulinum toxin treatment. The study comprised of a retrospective chart review on eligible patients and included information on patient demographics, responses, cannabis history...
Managing orbital compartment syndrome
This experimental study using cadaveric models was done to evaluate the surgical technique effective in relieving orbital compartment syndrome. Twelve cadaveric orbits were injected with blood analogue stained with fluorescein. Pressure probes were inserted in superotemporal (advanced 40mm into orbit)...
Blepharokeratoconjunctivitis treatment consensus
This study reports the results of a Delphi consensus method to develop a pragmatic approach to BKC treatment in children. A major limitation to the study was the involvement of only four clinicians. Four rounds in total were completed to...
IOL cataract surgery in seven to 24 month olds
The purpose of this study was to present the long-term outcome of IOLs in paediatric patients who received cataract surgery aged seven to <24 months. This was retrospective study with minimum follow-up of 12 months for 27 patients (28 eyes)....
Screening to detect high hyperopia
The purpose of this study was to compare the effectiveness of the plus lens test versus the Spot vision screener. This was a prospective study and 109 children aged two to 12 years (62% female) underwent both assessments followed by...
IXT control vs. binocular summation
The purpose of this study was to evaluate the relationship of BS scores with other current markers used for evaluating the control in preoperative intermittent exotropia (IXT) patients. Data was collected on stereoacuity, angle of deviation, Newcastle control score (NCS),...
