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A case of Miller Fisher Syndrome and bilateral asymmetric globe retraction

1 February 2022 | | EYE - Neuro-ophthalmology, EYE - General
Miller Fisher syndrome (MFS) is a rare, acquired nerve disease that is considered to be a variant of Guillain-Barré syndrome. It was first recognised by James Collier in 1932 as a clinical triad of ataxia, areflexia and ophthalmoplegia. Later, it...

Dramatic myopic shift due to epithelial basement membrane dystrophy

3 October 2024 | | EYE - Cornea
Epithelial basement membrane dystrophy (EBMD), also known as map-dot-fingerprint dystrophy, is a common anterior corneal disorder affecting approximately 2% of the population [1]. It is characterised by the abnormal maintenance of the basement membrane, resulting in protrusions into the epithelium....

Transferring imaging from primary to secondary care (part 2)

5 October 2020 | | EYE - General
Transferring clinical imaging from high street optometrists to secondary care is an increasingly requested option, especially in the context of the COVID-19 pandemic. A wide variety of solutions exist to allow this, each with their own merits and shortcomings. In...

The adverse effects of COVID-19 on undergraduate ophthalmology education: An opportunity to reform ophthalmology training

11 January 2021 | | EYE - General
The steady erosion of undergraduate ophthalmology teaching, which has been acutely exacerbated by the COVID-19 crisis, has led to a lack of basic ophthalmology examining skills and knowledge amongst clinicians of other specialities. Concurrently, there has been a rise in...

DMEK vs. UT-DSAEK: has the debate been finally concluded?

1 October 2021 | | EYE - Cornea, EYE - General
In recent years the surgical treatment of corneal endothelial dystrophy has progressed tremendously. Descemet’s membrane endothelial keratoplasty (DMEK) is the newest iteration in the line of rapid surgical advances that has taken place. However, the previously accepted gold standard prior...

My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Getting one’s eye in

4 February 2021 | | EYE - General
Lisette Bijma, Sister in the Eye Emergency Department at John Radcliffe Hospital, explains how COVID-19 provided a ‘baptism by fire’ and enabled fundamental and positive changes to the running of the department. Five years ago, I arrived in the UK,...

Doctor at large

1 October 2021 | | EYE - Vitreo-Retinal, EYE - General
“In 1930, the Republican-controlled House of Representatives, in an effort to alleviate the effects of the… Anyone? Anyone?... the Great Depression, passed the… Anyone? Anyone? The tariff bill? The Hawley-Smoot Tariff Act? Which, anyone…?” In this memorable scene, the monotonous...

My Top Five: Promising gene therapies for ocular conditions

4 December 2024 | | EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

5 February 2020 | | EYE - Vitreo-Retinal, EYE - General
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Telemedicine strategies in ophthalmology: harnessing established and emerging technologies for lasting solutions

7 December 2020 | | EYE - Vitreo-Retinal, EYE - Imaging, EYE - Oculoplastic, EYE - General
The author considers recent progress and shares insights from leading practitioners in telemedicine applications and digital technology strategies. Amidst COVID-19 and combined mitigation and suppression measures, hospitals and clinics have responded rapidly to strengthen telemedicine strategies and virtual healthcare services...

Anisometropia following cataract surgery and its non-surgical treatment

1 April 2015 | | EYE - Cataract, EYE - Refractive
The desired result of cataract surgery is improved visual acuity without the use of spectacles. In practice most patients following initial cataract extraction are likely to be symptomatic of anisometropia giving rise to prismatic effects (anisophoria) and unequal retinal image...