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The long-term effects of AREDS on AMD progression

1 December 2013 | | EYE - Vitreo-Retinal
The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...

Brolucizumab in age-related macular degeneration, HAWK Study

3 October 2023 | | EYE - Vitreo-Retinal | Neovascular age-related macular degeneration, aflibercept, anti-vascular endothelial growth factor therapy, brolucizumab, commercial formulation
The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

MPH treatment effect in ADHD on choroidal vascular index

2 August 2024 | | EYE - Paediatrics, EYE - Strabismus
In this study the authors aimed to investigate the choroidal vascular index (CVI) in treatment-free children with ADHD, children regularly taking methylphenidate (MPH) and healthy controls. This was a prospective cross-sectional study of 52 patients with newly diagnosed ADHD, 46...
Journal of Neuro-Ophthalmology cover image.

Acromegaly associated with enlargement of extraocular recti muscles

3 October 2024 | | EYE - Neuro-ophthalmology
This retrospective case review aimed to evaluate the frequency and extent of extraocular muscle enlargement in cases of acromegaly at presentation. All new presentations of acromegaly diagnosis at a single tertiary centre over a five-year period were screened for inclusion....

World-first platform for transparent, fair and equitable use of AI in healthcare

25 November 2025 | artificial intelligence, diabetes, diagnostics, research
Revolutionary AI platform for detecting diabetic eye disease proven safe for NHS. Researchers have developed the world’s first real-world head-to-head testing platform to determine whether commercial artificial intelligence (AI) algorithms are fit for NHS use to detect disease in a...

Choroidal thickness in ocular sarcoidosis by OCT measurement

1 December 2014 | | EYE - Vitreo-Retinal
This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...

Effects of blood donation on the physiology of the eye

1 December 2018 | | EYE - Vitreo-Retinal
Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...

ROP anti-VEGF treatment review

3 June 2021 | | EYE - Paediatrics, EYE - Strabismus
The purpose of this review was to consider data relating to risks and benefits of the use of anti-VEGF treatment for retinopathy of prematurity (ROP) over the past five years of 2015-2020. Ocular benefits include treatment of aggressive posterior ROP,...

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

1 February 2017 | | EYE - Oncology
Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

The College of Optometrists welcomes recommendations to increase support for NHS eyecare costs

30 April 2025 | optometry, optometrists, infrastructure, financial support, news
Sarah Cant, Director of Policy and Strategy, The College of Optometrists, commented: “The College of Optometrists welcomes Healthwatch England’s recommendations to increase the support available for people on low incomes so that they can meet the costs of eyecare, a...

100 years since Sir William Duke-Elder graduated from the University of St Andrews

2 February 2024 | | EYE - General
With sincere thanks to Andrew King, Ophthalmic Optician and owner of Andrew King Opticians near Glasgow, for his extensive research into Duke-Elder’s life.' Sir William Stewart Duke-Elder. Photo credit: Edward Irvine Halliday, Institute of Ophthalmology. In the world of ophthalmology,...

Moorfields Education: Biometry study day April 26

18 April 2026
This one-day in-person study day has been designed to meet the training needs of nurses, nursing associates, technicians, and anyone with an interest to improve their knowledge and understanding of biometry and its calculation and reading a biometry report. The...