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Conjunctival inflammation in glaucoma patients
Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...
RPE use similar pathway to regulatory T cells to inhibit immune response
Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....
Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience
Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...
Smartphone use and its effects on eyes
Longitudinal pilot study on 12 young healthy adults comparing effects of smartphone use over a 60-minute period. Reading conditions and smartphone use was standardised for all participants. Ocular symptoms, tear function and binocular vision were assessed before and after each...
Complications after cataract surgery in high myopes: a systematic review and meta-analysis
The authors review all the modern literature on complications after phacoemulsification in high myopes with axial lengths (AL) greater than 25.0mm. Twenty-eight studies reporting on 19,586 eyes were included. The corrected distance visual acuity (CDVA) improved from 0.96 ± 0.53...
Yolk sac tumours of the orbit and sinonasal tract
This paper outlines two case reports of patients with yolk sac tumours (YSTs) and carries out a review of the literature on this rare malignancy. YSTs are a type of germ cell tumour and primarily occur in the gonads. Ten...
Vigabatrin-induced retinal toxicity detected by 30Hz ERG
The purpose of this study was to assess the role of 30Hz flicker electroretinogram (ERG) as a marker for measuring changes in visual function over time in children receiving vigabatrin. This was an observational study of 11 children with mean...The Arclight: A ‘pocket’ ophthalmoscope to revitalise undergraduate teaching?
Ophthalmoscopy should be a core skill for every doctor and should be firmly embedded in the undergraduate curriculum similar to the unquestioned position of the stethoscope. The simplicity of the Arclight means it is easy to useand, importantly, to learn...Building research capacity through the VISION 2020 LINKS Programme
The aim is to build capacity for research in the region covered by the College of Ophthalmology of Eastern, Central and Southern Africa (COECSA). The project will build research capacity in three ophthalmology training institutions by ‘training the trainers’ and...NHS Practitioner Health releases National Guide for Health and Care Professionals Affected by Suicide
To mark the second year of the UK’s National Suicide Memorial Day for Health and Care Workers, NHS Practitioner Health will launch a suicide prevention and postvention navigation guide for health and care professionals. The National Suicide Memorial Day for...Moorfields Education: Dilemmas in periocular and orbital tumour management
This course is an international collaboration between Moorfields Eye Hospital, London and MD Anderson Cancer Center, Houston, bringing you the latest research and practice in periocular and orbital oncology. .
