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The challenge of chorioretinal folds in virtual eye clinics

Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...

Multimodal imaging in wet AMD

This novel study set out to determine grader agreement levels of various retinal imaging techniques, commonly used in the diagnosis of wet age-related macular degeneration (AMD). Images from 52 eyes were by examined by two different observers. All images were...

Changes in corneal endothelial layer after strabismus surgery

The purpose of this study was to investigate the changes in the corneal endothelial layer by specular microscopy after surgery in patients with horizontal and oblique strabismus. Eighty-three eyes of 56 patients were evaluated prospectively. There were three subgroups: one...

Neuroanatomical structures and eye movements

The aim of this study was to review and critically discuss the role of ocular proprioception in oculomotor control and development of eye motility disorders. The authors considered proprioception, structure and proprioceptors of eye muscles, singly and multiply innervated muscle...

Life in the glaucoma laboratory

When people ask me what life in the laboratory is really like, I often pause. On one hand, it is the romantic notion of pushing back the boundaries of science with the daily rhythm of experiments, data and easily obtained...

Optical quality difference between monofocal and multifocal intraocular lenses

It is well known that multifocal intraocular lenses (IOLs) can generate more than one focus to restore distance and near vision, but patients may experience adverse optical phenomena such as decreased contrast sensitivity and induced glare or halos. The authors...

Two bifocals and a trifocal

The authors compare the optical outcomes of two bifocal intraocular lenses (AcrySof ReSTOR +2.50 Diopter [D] add +3.0D add) with a trifocal lens (AT LISA tri 839MP). The optical qualities of the lenses were quantified by measuring the modulation transfer...

General purpose AI: Transitioning from high performance in highly curated settings to useful applications in ophthalmology

Artificial intelligence (AI) may be understood as the ability of machines to perform tasks which otherwise require human perception, reasoning, or learning. With the advent of deep learning, AI has achieved remarkable results across a wide range of medical tasks...

Stereotactic radiotherapy for polypoidal choroidal vasculopathy

Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular AMD. It is a disease of choroidal vasculature characterised by abnormal branching vascular network with aneurysmal dilatations (polyps). Features of PCV include pigment epithelial detachments (PED), subretinal fluid (SRF) accumulation and...

A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model

This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...

Ologen Collagen Matrix to treat ocular hypotony after filtration glaucoma surgery

The authors report a retrospective, observational case series of a Japanese cohort. 12 consecutive implantations of ologen in nine eyes of nine subjects (five men, four women; mean age ±SD, 72.1±12.7 years) who underwent subconjunctival implantation of the device to...

FOUNDATIONS OF INTRAOCULAR MICROSURGERY – Principles for Elite Performance Volume 1: Systemic Challenges

Cataract surgery is the most commonly performed intraocular surgery performed in the UK. It takes years of meticulous practice and experience to master the surgery and become a safe and slick surgeon. As the saying goes, “forewarned is forearmed.” Anticipating...