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ESASO Course Series Vol. 4 Optical Coherence Tomography

This book, which is the latest volume from the European School for Advanced Studies in Ophthalmology (ESASO) course series, is a revelation and joy to review. This compact volume provides an introduction and an update to the most recent technological...

Ocular surface in donor eyes after CLAU

This retrospective study examined ocular surface stability of donor eyes following conjunctival limbal autografts (CLAU). Forty-five eyes underwent CLAU with chemical burns being the most common indication. All but two eyes had just over 4 o’clock hours of CLAU segment...

Risk factors for intraoperative floppy iris syndrome

Intraoperative floppy iris syndrome (IFIS) is charcterised by flaccid iris stroma leading to fluttering and billowing of iris, tendency of iris to prolapse through surgical incisions and causing intraoperative pupil constriction. IFIS is characterised as complete when all three features...

Late stromal rejection in DALK

This case series reported on late stromal rejections in eyes after uncomplicated deep anterior lamellar keratoplasties (DALKs). Four eyes of three patients experienced episodes of isolated stromal rejection 33 to 46 months after surgically uncomplicated DALKs and a minimum of...

Macular hole postop positioning

The purpose of this study was to determine whether the full thickness macular hole (FTMH) closure rate with nonsupine positioning (NSP) is noninferior to the high closure rate achievable with face down positioning (FDP). All patients were pseudophakic pre macular...

Boston type I keratoprosthesis for limbal stem cell deficiency

Boston type I keratoprosthesis (KPro) long-term outcomes were compared in patients with and without limbal stem cell deficiency (LSCD) in this retrospective study. In the 11 year period 68 procedures were performed in individuals with LSCD, and 105 procedures in...

Froben for anterior scleritis

Flurbiprofen (Froben) is one of the nonselective cyclooxygenase (COX) inhibitors blocking both COX-1 and COX-2 pathways. Agrawal et al. undertook a retrospective cohort study to determine the effectiveness of oral Froben in managing noninfectious, non-necrotising anterior scleritis. One hundred and...

Prostaglandin-associated periorbitopathy

This is a masked study of 33 patients who had been taking a prostaglandin analogue in one eye only for at least a year, to look for signs of prostaglandin-associated periorbitopathy (PAP). The investigators devised a new grading system to...

Tear film thickness after treatment with artificial tears in patients with moderate dry eye disease

In recent years artificial tear drops addressing tear film osmolarity have come onto the market. Increased tear evaporation and reduced tear volume results in tear hyperosmolarity. This triggers an inflammatory process leading to apoptosis of goblet and epithelial cells. Trehalose,...

Three years of experience with quantiferon-TB Gold Testing in patients with uveitis

Quantiferon-TB Gold is a new alternative to the tuberculin skin test that utilises synthetic peptides representing M. tuberculosis antigens ESAT-6, CFP-10, TB7.7 and upon incubation with whole blood IFN-γ is released from pre-sensitised T cells and can be measured by...

Intravitreal injection related endophthalmitis

This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...

Antibiotic prophylaxis after intravitreal injections

The use of topical antibiotics as prophylaxis after intravitreal injections is a contentious issue, especially now with increasing use of intravitreal anti-VEGF agents. In the Wills Eye Institute, prior to May 2011, all patients undergoing intravitreal injections in the office...