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Unusual case presentation of arteritic anterior ischaemic optic neuropathy

The authors present a single case of an 84-year-old man with arteritic anterior ischaemic optic neuropathy, but with unusual features on temporal artery biopsy. He presented with a three-day history of sudden onset of loss of vision in his right...

Experiences of patients and their families and the impact of Leber hereditary optic neuropathy

The authors present a qualitative study which aimed to explore the impact of Leber hereditary optic neuropathy (LHON) from diagnosis to present day on both patients and their families. Individuals with LHON and their families were purposively sampled from four...

A review of the risk of nonarteritic anterior ischaemic optic neuropathy post-cataract surgery

A systematic review and meta-analysis are presented with the aim of assessing whether cataract surgery increases the risk of non-arteritic anterior ischaemic optic neuropathy (NAION) and identify potential predictors of risk. The search strategy components are outlined in detail. A...

Leber’s hereditary optic neuropathy outcomes in an Indian population

A large cohort study in an Indian population is presented, with clinical and genetic profile analysis of patients with Leber’s hereditary optic neuropathy (LHON) treated over a five-year period. The study included 157 patients; 143 male, 14 female (10.2:1 ratio)...

Leber’s hereditary optic neuropathy: from lab to clinic

Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...

Is optic disc drusen a risk factor in young patients with anterior ischaemic optic neuropathy?

This retrospective cross-section multicentre study reviewed 65 patients all younger than 50-years-old with non-arteritic anterior optic neuropathy (NA-AION) between April 2017 and March 2019. The purpose of this study was to investigate if there was a link between Optic Disc...

Do occult neuroretinitis and non-arteritic anterior ischaemic optic neuropathy differ in presentation?

This study evaluates differences between neuroretinitis and non-arteritic anterior ischaemic optic neuropathy (NAAION) in terms of patient demographics, clinical presentation, and optical coherence tomography (OCT) findings. Medical records of patients with a final diagnosis of occult neuroretinitis or NAAION were...

Diabetic polyneuropathy and risk of developing diabetic retinopathy

Diabetic polyneuropathy (DPN), diabetic retinopathy (DR) and diabetic nephropathy are widely classified as microvascular complications of diabetes. DPN, which may cause complete sensation loss, is another common complication of DM. The DPN-related diminished sensation presents a significant risk factor for...

A novel way to diagnose optic neuropathies using Bruch’s membrane opening

Differential diagnosis of optic neuropathies can be challenging but is crucial for the correct management of the underlying disease and prevention of further damage. Bruch’s membrane opening (BMO) was recently discovered as the anatomical border of the optic disc. BMO...

Local surgical treatment of trigeminal neuralgia

This is a retrospective review of a new surgical treatment of intractable periorbital neuropathic pain. Five patients with post-herpetic (three), post-traumatic (one) and idiopathic (one) neuralgia underwent transection of the nerves supplying the dermatomes affected by the neuropathic pain. The...

Repeated orbital decompression surgery

This is a retrospective review of nine redo orbital decompressions in six patients. All operations were performed for dysthyroid optic neuropathy, both initially and when repeated. The interval between first and redo decompressions varied from one to 15 years and...

Differences in elastometry of cornea and optic nerve head in both eyes of patients with NAION

Non-arteritic anterior ischaemic optic neuropathy (NAION) is an important cause of visual loss in the middle aged and elderly population. This prospective cross-sectional study investigates the biomechanical properties of optic nerve head (ONH) and cornea in both eyes of patients...