You searched for "Idiopathic"
Do operative interventions for IIH improve visual function?
1 April 2015
| Claire Howard
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EYE - Neuro-ophthalmology
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Idiopathic intracranial hypertension, lumboperitoneal shunt, ventriculoperitoneal shunt, visual fields
The authors of this paper reviewed patient case notes to determine visual outcome following shunt surgery for idiopathic intracranial hypertension (IIH). A retrospective case notes review was conducted for 50 patients who underwent shunt surgery for IIH. Outcome measures included...
IINS function
This study explored the impact of idiopathic infantile nystagmus syndrome (IINS) on quality of life in adults measured using the VFQ25 questionnaire. Of 38 subjects, 35 completed the questionnaire. Mean age was 35.1±13.0 years; 15 were British Caucasian and 14...Contact lenses for adults with infantile nystagmus
A pilot randomised controlled trial (RCT) was conducted to determine recruitment rates, acceptability of and adherence to treatment and adverse events along with change in best corrected visual acuity (BCVA) and nystagmus parameters from baseline to two weeks follow-up. The...Uveitis and juvenile arthritis costs
The purpose of this study was to evaluate whether cost, prior insurance authorisation concerns and subspecialty practice influence therapeutic decisions in the treatment of uveitis associated with JIA. The authors developed an email questionnaire that included a brief vignette of...Eyelid nodule outcomes
Idiopathic facial aseptic granuloma (IFAG) is a recently defined paediatric dermatology disorder. This study presents the clinical outcomes of children with IFAG nodules on their eyelids with or without facial nodules and aim to compare the outcomes with those presenting...Understanding retinal ciliopathy through Bardet-Biedl syndrome
5 August 2022
| Zhihang Cheng
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EYE - Vitreo-Retinal
This is a review article looking at up-to-date understanding and ongoing research in retinal ciliopathies. Syndromic ciliopathies consist of a group of disorders caused by ciliary dysfunction or abnormal ciliogenesis. These disorders have multiorgan involvement in addition to retinal degeneration...
Predicting outcome for visual acuity in optic neuritis associated with multiple sclerosis
3 October 2024
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a retrospective cohort study to evaluate key predictors of long-term high-contrast visual acuity following optic neuritis associated with multiple sclerosis. All patients coded as optic neuropathy and assessed by a neuro-ophthalmologist over a 10-year period were screened...
Preoperative RPE alterations in macular holes
1 April 2017
| Saruban Pasu
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EYE - Vitreo-Retinal
This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...
Macular atrophy with aflibercept
1 October 2018
| Saruban Pasu
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EYE - Vitreo-Retinal
The authors of this paper set out to investigate the prevalence of macular atrophy in treatment-naive patients with neovascular AMD undergoing aflibercept monotherapy (three monthly loading injections followed by subsequent treatment every two months). Case notes over a three year...
Should we be looking for anemia in the presence of papilloedema?
4 December 2023
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present a retrospective case notes review of patients diagnosed with idiopathic intracranial hypertension (IIH) presenting to a tertiary neuro-ophthalmology clinic over a 32-month period. The IIH group were age and sex matched with other patients attending the clinic...
Using lumbar puncture as a diagnostic tool of IIH when the presentation is typical
1 December 2021
| Lauren R Hepworth
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EYE - Neuro-ophthalmology
The authors present the findings of a retrospective observational chart review across three neuro-ophthalmology clinics. Databases at each clinic were searched using inclusion criteria based on established diagnostic criteria for idiopathic intracranial hypertension (IIH). Cases with missing data, atypical findings...
Investigating MOG-IgG as a cause for optic perineuritis
5 August 2020
| Claire Howard
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EYE - Neuro-ophthalmology
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Optic perineuritis, myelin oligodendrocyte glycoprotein (MOG), aquaporin-4 (AQP4), optic neuritis, optic nerve sheath
Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but in most cases is considered idiopathic. Diagnosis is established by magnetic resonance imaging (MRI) with the demonstration of optic nerve sheath enhancement with sparing of the optic...