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What's trending Oct/Nov 2019
#probeyeotic #eyeballbugs #microbiome The human microbiome usually conjures up images of the gastrointestinal tract and yoghurt containing good bacteria. However, research suggests that the ocular mucosa is home to a unique microbe collection, with important immunological functional properties [1]. This...
Management of congenital NLD obstruction
The authors evaluated changes in management of congenital nasolacrimal duct obstruction (CNLDO) by surveying 1495 Association for Paediatric Ophthalmology & Strabismus (AAPOS) members. The survey consisted of 21 multiple choice questions with anonymised return. Responses were received from 127 members...
Hybrid free vision screening for at-risk, low-income families
Give Kids Sight Day (GKSD) is an outreach programme at Wills Eye Hospital to provide free vision screening, ophthalmic examinations and glasses. It started in 2009 and has seen >11,000 children. Its primary aim is to reach high-risk families including...
Retinitis pigmentosa (RP) associated cystoid macular oedema (CMO)
This is a review article from two units in the UK and Australia, highlighting the supporting evidence of possible pathogenesis and treatment modalities of CMO in RP. The authors proposed that the likely mechanisms for RP-CMO involved the breakdown of...
RPE use similar pathway to regulatory T cells to inhibit immune response
Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....
HtrA1 enhances cell senescence
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...
Piggyback toric IOLs in complex cases
This study evaluates the outcome of toric sulcus fixated lenses (MS 614/714 TPB (Human Optics, Germany) in 21 eyes with high astigmatism. The cases included previous penetrating keratoplasty (n=15), post cataract surgery astigmatism (n=3), rotation of in-the-bag toric IOL (n=1),...
Dead bag syndrome: a new and rare cause of late IOL dislocation
The dead bag syndrome has recently been described as a cause of late spontaneous intraocular lens (IOL) subluxation and / or dislocation. The capsular bag remains clear years after surgery and then becomes diaphanous and floppy. The authors explanted seven...
A paradigm shift: re-defining success in retinal detachment repair
The authors describe in this review article that functional outcomes vary with surgical technique for retinal detachment repair. Traditional definitions of surgical success have been shifted due to advances in imaging techniques. Assessment of the integrity of retinal reattachment including...
