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Beyond vision loss: Why doctors should know about Charles Bonnet Syndrome

Over 250 years have passed since Charles Bonnet’s seminal essay, in which he described the symptoms of the syndrome that now takes his name [1]. Charles Bonnet Syndrome (CBS) describes the occurrence of visual hallucinations in people with significant visual...

Corneal dystrophies simplified

Based on biomicroscopic and histopathologic features, corneal dystrophies can be broadly classified into epithelial, Bowman’s layer / anterior stromal, stromal, and endothelial dystrophies. Corneal dystrophies are a group of inherited, bilateral, gradually progressing, non- inflammatory conditions caused by accumulation of...

Reflections on a twelve-year partnership: The Makassar-Dundee LINK

In the first article of a two-part series (see Part 2 here), the authors provide an overview of this hugely successful partnership and how they overcame the challenges of COVID-19. What began in 2008 as a connection between equals, has...

Emerging developments in dry eye

An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...

World ROP Congress 2025

The World Retinopathy of Prematurity (ROP) Congress 2025

Association between neurodegeneration and macular perfusion in the progression of diabetic retinopathy

In this prospective three-year longitudinal study, the authors aimed to explore the relation between retinal neurodegenerative changes and vessel closure (VC) in individuals with non-proliferative diabetic retinopathy (NPDR). The participants included 74 individuals with type 2 diabetes, NPDR, and Early...

Providing primary eyecare services during a global pandemic: the new normal

It would be fair to say that 2020 hasn’t quite turned out to be the year that anyone predicted. Living with a global pandemic has become our reality and we are having to get used to many aspects of our...

SOS (Simplified Ophthalmic Statistics) Part 3: Which statistical test should I use (if any)?

P<0.05 is a statement that brings joy to many researchers. Arguably this is because inclusion of such a statement may increase the chance of acceptance for publication. Whilst statisticians and non-statisticians are united in trying to change this culture, cultural...

Topography-guided photorefractive keratectomy in the treatment of corneal scarring

This study reports the outcome of topography-guided photorefractive keratectomy (TG-PRK) in the treatment of patients with corneal scarring. A retrospective case series including six eyes of six patients with corneal scarring and irregular astigmatism who underwent topography guided PRK. The...

Vision loss during Eylea treatment for AMD

This report investigated patients who lost more than two lines of vision despite periodic injections of aflibercept and explored the factors associated with vision loss. One hundred and ninety-six eyes were included in this study over a two year period....

Cataract surgery in patients being treated for neovascular AMD

This retrospective matched case control study evaluated outcomes and predictive factors of visual acuity (VA) change after cataract surgery in patients being treated for neovascular age related macular degeneration (nAMD). They compared 124 patients that had cataract surgery with 372...

First NHS Trust in North East of England achieves prestigious RNIB employment accessibility award

South Tyneside and Sunderland NHS Foundation Trust has become the first NHS Trust in the north east of England to achieve the Royal National Institute of Blind People’s (RNIB) Visibly Better Employer Standard (VBE). The Trust, which runs a major...