You searched for "proptosis"

5536 results found

Systemic screening in adnexal lymphoma

This is a retrospective review of 119 patients diagnosed with ocular adnexal lymphoma, 85 of whom had primary adnexal disease and 34 had previously been diagnosed with lymphoma outside the ocular adnexa. Sixty-eight of the primary and 24 of the...

OCT measures of lateral and medial recti

The authors assessed the agreement of the measurements of the horizontal rectus muscle insertion distance to the limbus and the muscle thickness between three different OCT devices. This was a cross section observation study of 70 eyes of 35 subjects....

IAC vs. IVC chemotherapy for RB

This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...

Systemic pharmacology of intravitreal anti-VEGF

This study aimed to evaluate and compare serum drug concentrations and plasma free-VEGF concentrations in patients with AMD, DME, or RVO receiving intravitreal injections of aflibercept, bevacizumab or ranibizumab. This prospective study enrolled patients from several offices of a single...

Clinical characteristics and outcomes of open globe injury

This retrospective cohort study examined consecutive open globe injuries at a tertiary referral centre over a three year period. The aim of the study was to detail the clinical characteristics of open globe injuries and to explore their association with...

Phaco-ECP vs. Phaco alone to treat glaucoma

This retrospective review compared combined phacoemulsification and endoscopic cyclophotocoagulation (phaco-ECP) to phaco alone in patients with mild to moderate glaucoma. Outcome measures included cumulative full and qualified success survival, postintervention IOP and ocular anti-hypertensive medication reduction. Full success was defined...

A phase 3 randomised trial of nicotinamide for skin cancer chemoprevention

To B3, or not to B3? That was the question asked in this controlled trial in which the authors were able to show that oral nicotinamide (vitamin B3) is able to reduce further skin cancer development in high risk patients....

Neighbourhood deprivation and risk of age-related eye diseases

In this large epidemiological study, the authors sought to determine if neighbourhood wealth affects age-related ocular health. In particular they wished to see if there was a correlation between social deprivation and macular degeneration, cataract, diabetes-related eye complications, and glaucoma....

Twenty-four hour IOP patterns in patients with thyroid eye disease (OO/GL)

Elevated IOP in patients with thyroid eye disease (TED) can be caused by restriction and compression of the globe by enlarged extraocular muscles, elevated episcleral venous pressure and increased mucopolysaccharide deposition in the trabecular meshwork. Although previous studies have investigated...

Myopic choroidal neovascularisation

This is a review article summarising the latest myopic CNV (choroidal neovascularisation) literature in the clinical experience and management outcomes for recommendation algorithm. The aetiology of the myopic CNV was discussed by the authors under the heading of the heredo-degenerative...

Choroidal and RNFL thickness in patients with OSAS

In obstructive sleep apnoea syndrome (OSAS), hypoxia secondary to repetitive apnoeic episodes leads to blood pressure variations and haemodynamic changes. There is also intermittent activation of the sympathetic system when the patient is aroused from sleep during apnoeic episodes. OSAS...

Transfected RPE cells inhibit AMD in rats

Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. Wet AMD is characterised by choroidal neovascularisation, new vessels into the retina, leading to leakage and tissue damage. Many proangiogenic factors particularly vascular endothelial growth factor (VEGF)...