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Effect of preservative free fluoroquinolones on human corneal epithelial cells in vitro

1 October 2014 | | EYE - Cornea, EYE - General
Fluoroquinolones, including second generation (ofloxacin and ciprofloxacin), third generation (levofloxacin and tosufloxacin) and fourth generation (gatifloxacin and moxifloxacin), are a group of bactericidal agents used to treat multiple ocular infections. The third and fourth generation fluoroquinolones have enhanced Gram-positive activity...

Autophagy in lens mitochondria loss

1 April 2014 | | EYE - Cataract, EYE - Refractive | ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Corneal suture sample evaluation

1 February 2019 | | EYE - Cornea, EYE - General | cornea, infection, microbiology
This is a prospective study of 35 patients’ suture samples taken from a tertiary cornea clinic, Miami, Florida, with a history of penetrating keratoplasty. The aim is to study the relationship between corneal suture bacteriology, biofilm and the clinical setting,...

An alternative to povidone-iodine for intravitreal injections?

1 February 2017 | | EYE - Vitreo-Retinal
While povidone-iodine (5% aqueous) preparations have historically been considered the most effective antimicrobial prophylaxis for ophthalmic procedures and have been adopted as routine for intravitreal injections, post-procedure pain is a commonly recognized adverse event of IVI and has typically been...

Are we short-sighted about myopia?

1 December 2017 | | EYE - Cataract, EYE - Refractive, EYE - General
Worldwide prevalence of myopia has increased rapidly in recent years and has now reached epidemic levels, particularly in South-East Asia where prevalence is around 80% [1-4]. Myopia prevalence is also increasing in the United States and Europe where it is...

Is it NAION… Now what?

3 April 2024 | | EYE - Neuro-ophthalmology
Case presentation We present the case and discussion of a 46-year-old Caucasian male who complained of immediate reduced vision following complicated neck dissection including a total laryngopharyngectomy, free flap reconstruction for a T4N3 squamous cell carcinoma (SCC) of the left...

Digital eyecare – enabling better communication between primary and secondary care

3 June 2021 | | EYE - Imaging, EYE - General
Alexander Chiu and his co-authors highlight innovations influencing healthcare advancement and how trainees can get involved. Hospital eye services (HES) were under great pressure to meet demand, even before the COVID-19 pandemic. This pressure has increased with the cancellation and...

Supporting optical professions throughout the pandemic

1 December 2020
A letter has been released to go to all optical professionals on behalf of the professional bodies and government bodies responsible for ophthalmic dispensing and optometry.

Scotland's Bottle Deposit Return Scheme – have visually impaired people even been considered?

31 May 2023 | vision impairment, Sight Scotland, Sight Scotland Veterans
Sight Scotland and Sight Scotland Veterans have welcomed the delay to the Bottle Deposit Return Scheme and are urging the Scottish Government to use this time to consider the implications it will have for visually impaired people.

Primary care optometry poised to help demand on GPs

21 July 2023 | AOP, waiting times, optometry
The 2023 GP Patient Survey (GPPS) published last week shows a decline in the number of patients reporting a good overall experience with their GP practice.

Around 450,000 children disadvantaged by lack of school support for colour blindness

5 December 2024 | colour blindness, eyesight, SEND, education, children, school, book
Around 450,000 children are being failed by the UK education system because they have a special educational need and disability (SEND) that is effectively unrecognised by most schools and local education authorities, an author has warned. Supporting Colour Blindness in...

A practical guide to anisocoria

1 February 2018 | | EYE - Neuro-ophthalmology, EYE - General
Anisocoria means the presence of difference in the size of the right and left pupils. It is a sign of an abnormality in the efferent pathway. The first question facing the ophthalmologist is to ascertain if anisocoria is present or...