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1099 results found

Role of fundus autofluorescence patterns and baseline atrophy area on geographic atrophy progression

Central geographic atrophy (GA) is one of the morphological sub types of late-stage macular degeneration. The natural course of the disease is characterised by expanding areas of macular atrophy, which cause absolute scotoma. Fundus autofluorescence (FAF) is derived from lipofuscin...

Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)

The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...

Acetazolamide and CMO

The authors set out to analyse the effect of acetazolamide therapy on inflammatory cystoid macular oedema (CMO) as defined by change in central macular subfield thickness (CST), as well as its effect on visual acuity. A retrospective chart review was...

Retinal thickness and visual acuity change correlations after amblyopia occlusion therapy

This prospective study aimed to assess change in retinal nerve fibre layer (RNFL) and macular thickness, and clinical correlations with visual outcomes, after amblyopia treatment in 30 children with moderate to severe amblyopia. Mean age of children was 5.26 ±1.65...

Headaches in ophthalmology (part 2)

Ophthalmologists see a large number of patients with headaches or facial pain in the ophthalmic outpatient clinics or in emergency clinics. Over two articles, I will discuss several causes of headaches, ocular manifestations and proposed management and referral options. It...

Proning and the pandemic - ocular complications seen in critical care

Priyanka Sanghi and her co-authors explore the ocular complications seen in critical care units throughout the country as we treat patients through this challenging time. The SARS-Cov-2 (COVID-19) pandemic has placed the NHS and critical care services under immense strain,...

Corporate M&A pace gathers momentum

Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...

Cancer associated retinopathy

Abdul Muhyemin Tarin reviews the presentation, pathophysiology and management of this paraneoplastic syndrome. Case presentation A 60-year-old hypermetropic female patient presented with several months’ history of painless blurred vision. Visual acuity (VA) was 6/24 and 6/9-1 in right and left...

Apr/May 2017 Quiz

History A five-month-old baby was seen in clinic with bilateral congenital corneal opacities. The right cornea is shown in Figure 1. Figure 1. Examination revealed corneal oedema and opacities of Descemet’s membrane and endothelium with a few vesicular lesions. Corneal...

Cataract surgery in patients with Vogt-Koyanagi-Harada

This retrospective, interventional case series of 286 patients (408 eyes) assessed visual outcome and prognostic factors in patients with Vogt-Koyanagi-Harada (VKH) undergoing cataract surgery between September 2008 and December 2017. Two groups were reviewed. The first group (352 eyes) had...

Glaucoma diagnosis with spectral-domain OCT of GCL and IPL

This is a prospective, cross-sectional, observational study by the New York Eye and Ear Infirmary, which recruited normal subjects and glaucoma patients with a range of visual field loss representing various degrees of glaucomatous optic neuropathy. A total of 69...

Wet AMD outcomes post cataract surgery

The authors present the findings of a retrospective study looking at the progression of wet age-related macular degeneration (AMD) in patients who underwent cataract surgery. They recruited a series of 111 patients of which 38 were men and 73 were...