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Melkersson-Rosenthal syndrome

Melkersson-Rosenthal syndrome (MRS) is a rare neuro-mucocutaneous disorder which is defined by a triad of orofacial oedema, furrowing of the tongue, and recurrent episodes of facial nerve palsy [1]. Due to the rarity of the disease and inconsistent presentation, MRS...

Things I’d tell my medical school self, had I known my first year on the job would be during a global pandemic

In a conversation with his younger self, a foundation doctor reflects on the contrast between his expectations of medicine at university and the reality of working during the coronavirus pandemic. Every doctor arrives at medical school with nervous anticipation, yet...

NHS Practitioner Health: Providing you with the care you deserve

Healthcare professionals carry a unique weight: the responsibility for the lives and wellbeing of others. But who takes care of the caregivers? For over 15 years, NHS Practitioner Health has been doing just that – providing vital mental health and...

Home Wi-Fi / range and security tips

This issue covers two topics that relate to Wi-Fi. The first is keeping your wireless network secure and the second is extending its range. Keeping home Wi-Fi secure Let’s say the recent computer attacks that resulted in disruption to NHS...

World-first platform for transparent, fair and equitable use of AI in healthcare

Revolutionary AI platform for detecting diabetic eye disease proven safe for NHS. Researchers have developed the world’s first real-world head-to-head testing platform to determine whether commercial artificial intelligence (AI) algorithms are fit for NHS use to detect disease in a...

LASEK with mitomycin C to correct myopia in thin corneas

This study evaluated the long-term outcomes of laser-assisted subepithelial keratomileusis (LASEK) with intraoperative use of mitomycin C (MMC) performed on thin corneas for the correction of myopia. MMC modulates the corneal wound healing response in surface healing, thus reducing the...

Uveitis in HIV infected persons

Before the advent of highly active antiretroviral therapy (HAART), uveitis, in particular cytomegalovirus (CMV) retinitis, was the most common cause of visual loss in patients with AIDS. HAART has altered the cause of ocular disease in HIV infected individuals by...

Cavernous sinus thrombosis and orbital cellulitis

This is a report of six cases of combined orbital cellulitis and infective cavernous sinus thrombosis, with a literature review. The average age was 39 years, four were male and two were intravenous drug users. All had sinusitis, usually involving...

Cytokine levels in vitreous fluid in patients with pathological myopia

Pathological myopia (PM) is a leading cause of irreversible visual impairment worldwide, and efforts are dedicated to the study of its underlying mechanisms. Axial extension of the eyeball is regulated via a cascade of biochemical molecules that are initiated in...

Retrospective review of visual outcomes in Idiopathic intracranial hypertension (IIH)

Idiopathic intracranial hypertension (IIH) is a clinical syndrome characterised by headache and papilloedema that can lead to significant visual morbidity. IIH is diagnosed by the modified Dandy criteria, which include normal neuroimaging and cerebrospinal fluid (CSF) composition, high CSF opening...

Significant associations to presence of significant retinal haemorrhages in suspected child abuse

The authors aimed to extract statistically significant associations between non-ocular clinical and diagnostic imaging findings and the presence of significant retinal haemorrhages, and then develop an evidence-based screening algorithm to determine when to consult an ophthalmologist in suspected child abuse...

Experiences of patients and their families and the impact of Leber hereditary optic neuropathy

The authors present a qualitative study which aimed to explore the impact of Leber hereditary optic neuropathy (LHON) from diagnosis to present day on both patients and their families. Individuals with LHON and their families were purposively sampled from four...