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Review of pathogenesis of Acanthamoeba keratitis
In this review, the author summarised the current microbiomic and immunological evidence related to the pathogenesis of Acanthamoeba keratitis (AK). AK has been described for almost 50 years, but the exact biology of the disease remains perplexing. Acanthamoeba spp. are...
Cutaneous malignant melanoma metastasis to pseudophakic lens
Metastases to the eye and orbit are rare and intraocular cutaneous malignant melanoma metastasis (ICMM) is exceedingly rare, representing around 5%. There have only been three previous cases of ICMM to the lens in the literature, all of which presented...
Oculofacial plastic surgery – is antibiotic prophylaxis required?
This is a randomised, controlled, unmasked clinical trial evaluating whether topical antibiotic prophylaxis reduces the rate of infection after oculofacial plastic surgery compared to a non-antibiotic ointment. A total of 401 participants over the age of 18 were recruited, with...
Anterior ischaemic optic neuropathy post cataract surgery
This retrospective population-based cohort study assessed whether there was an increased incidence of anterior ischaemic optic neuropathy (AION) post cataract surgery compared to patients that had not had cataract surgery. They reviewed the notes of all patients diagnosed with AION...
Efficacy and safety of novel PF brimonidine / timolol fixed-combination ophthalmic solution for OAG
This study is a multicentre, randomised, open-label, parallel-group clinical trial to evaluate the efficacy and safety of a newly developed preservative-free (PF) brimonidine / timolol fixed-combination (BTFC) ophthalmic solutions as compared with preservative-containing (PC) BTFC ophthalmic solution in adult patients...
Visual outcomes after surgery for primary rhegmatogenous retinal detachment in era of microincision vitrectomy
This is a prospective, multicentre, nationwide study between 2016 and 2017, to investigate the preoperative ocular factors, surgical techniques (pars plana vitrectomy (PPV) or scleral buckling (SB), or combined procedures) for rhegmatogenous retinal detachment (RRD) and postoperative best corrected visual...
Effect of postoperative swelling on lid surgery outcomes
This is a review of patients undergoing upper lid external levator resection ptosis surgery or blepharoplasty, to assess whether the degree of early postoperative swelling affects the final lid position. Twenty-five patients undergoing ptosis surgery and 29 upper lid blepharoplasty...
YouTube videos for strabismus information
The aim of this study was to assess the quality, reliability and popularity of YouTube videos addressing strabismus. The authors searched YouTube using keywords of strabismus, squint, eye squint and crossed eye. The top 50 for each search were taken;...
Topical anaesthetic strabismus surgery
This prospective observation study was undertaken with 16 symptomatic diplopia patients (15 male, one female) from various causes. All underwent single stage adjustable strabismus surgery (SSASS) under topical anaesthesia. Mean age was 28.12 years (range 19-65) and all had a...
Surgical outcomes for constant and intermittent exotropia
This study evaluated the surgical results for constant and intermittent exotropia to investigate the factors that might influence the surgical results in a Scandinavian population. This was a retrospective study from 2011-2015 during which time 633 patients had strabismus surgery...
OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema
This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....
