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Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy
Researchers identify a novel genetic cause of Fuchs endothelial corneal dystrophy, offering new ways for future therapies to target this common, age-related cause of visual loss. In a landmark study, researchers supported by NIHR Moorfields Biomedical Research Centre, have identified...
Secondary iris-claw anterior chamber lens implantation in patients with aphakia without capsular support
This retrospective, non-randomised, non-comparative, interventional study including 128 eyes of 124 patients that presented with aphakia with no capsular support. All patients consecutively underwent Artisan iris-claw intraocular lense (IOL) implantation between 1997 and 2010. The inclusion criteria were: aphakic without...
Can intravitreal anti-VEGF injections affect corneal nerves?
This was a retrospective case-control study looking at the effect of anti-VEGF injections on corneal nerves (CN). Fifty-seven patients with a history of at least three anti-VEGF injections in one or both eyes and available confocal microscopic imaging were included...The Worshipful Company of Spectacle Makers awards two Master’s Medals for early career research
The Worshipful Company of Spectacle Makers (WCSM) this week announced the winners of two Master’s Medals for 2025. Fabian Yii from Edinburgh was awarded the Master’s Medal for his paper, 'Fundus Refraction Offset as a Personalized Biomarker for 12-Year Risk...Aug/Sep 2017 Quiz
History A seven-year-old atopic boy has been treated for phlyctenulosis with mild topical steroids. However, he developed dramatic changes at the right limbus in two weeks. He also had past history of vernal keratoconjunctivitis (VKC) with poor compliance to treatment....Aug/Sep 2015 Quiz 1
History A 60-year-old woman was referred to ophthalmology with a suspected left eye choroidal naevus. Visual acuity was unaffected in both eyes and she was asymptomatic. Ocular history and medical history were unremarkable. Questions Figure 1: Fundus photograph. 1. What...
Ozurdex in epiretinal membrane surgery
This was a prospective multicentre pilot study, looking at the effect of Ozurdex on visual acuity (VA) and central retinal thickness (CRT) in patients undergoing surgery for epiretinal membrane (ERM). Twelve eyes of 12 patients were included in the study....Moorfields cataract, medical retina and disc assessment
The Cataract/medical retina/ disc assessment short course has been designed to meet the training needs of band 6’s and 7s who wish to develop their knowledge and skills in disease recognition, management and intervention of cataract, medical retina and disc...
Impact on the corneal and anterior chamber characteristics after femtosecond laser cataract surgery
Femtosecond laser cataract surgery (FLACS) is being increasingly used in the preparation for cataract surgery. Benefits of circular capsulorrhexis and reduced phacoemulsification energy have been shown in the literature. This study was designed to assess the anterior chamber characteristics and...
Somatostatin protects retinal pericytes
Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...
Is an increased homocysteine level associated with greater risk of AMD?
Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...
