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Ablepharon-macrostomia syndrome
The ablepharon-macrostomia syndrome is a very rare condition caused by a dominant mutation in the TWIST2 gene. Congenital defects include rudimentary eyelids, macrostomia, ambiguous genitalia and campodactyly. Neonates are at risk of severe corneal exposure without intervention. Previous reports have...
Visual field progression after glaucoma drainage device implantation
This retrospective interventional case series assessed changes to visual fields after implantation of a glaucoma drainage device (Baerveldt, Ahmed or Molteno Devices) between 2010 and 2015. A total of 106 eyes from 96 patients were included in the final analysis...
Long-term outcome of scleral-sutured posterior chamber intraocular lens
This is a retrospective review of 392 consecutive cases in 349 patients who had scleral-sutured intraocular lens (IOL) due to aphakia, subluxated or luxated IOL, over a 10-year period in one centre from Barcelona. Preop and postop data were collected...
Surgical outcome for cyclic strabismus
The aim of this study was to report the outcome of surgical treatment in a series of seven cases of paediatric cyclic strabismus. This was a retrospective study of children with surgical treatment for the manifest cyclic deviation. Six children...
Laser photocoagulation vs. intravitreal (IVT) aflibercept for ROP
The efficacy, recurrence rate and requirement for additional treatment were compared between laser photocoagulation and IVT of 1mg/0.025ml aflibercept in the treatment of retinopathy of prematurity (ROP). The study included 27 babies (51 eyes) who completed a follow-up period after...
ISBCS versus DSBCS
This is a retrospective study of 53 children who had immediate sequential bilateral cataract surgery (ISBCS) (37/53) or delayed sequential bilateral cataract surgery (DSBCS) (16/53) at a tertiary referral paediatric hospital in Toronto, Canada. Clear visual axis was the measure...
Effect of one versus 24 hours diagnostic occlusion
The purpose of this study was to compare measurements taken after one and 24 hours of diagnostic occlusion in cases of basic and divergence excess types of intermittent exotropia. This was a prospective study of 43 patients (34 females) with...
Ocular damage from laser pointers
This retrospective study of case notes from a tertiary eye centre over a five-year period, recruited nine children (12 eyes: eight boys) aged 9-15 years. Three presented with deteriorating vision whilst others had retinal changes noted as incidental findings at...
Histopathology-guided management of ocular surface squamous neoplasia (OSSN) with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy
This is a retrospective interventional consecutive case series of 42 eyes of 42 patients with OSSN with histopathologically proven corneal stromal and / or scleral invasion following excision biopsy. The mean tumour basal diameter was 9.3mm and thickness of 3.1mm...
Refractive surgery for anisometropic amblyopia
The authors report the outcomes of refractive surgery with phakic intraocular lens (PIOL) implant for management of anisometropic amblyopia in children intolerant to conventional therapy. This was a retrospective study of 71 eyes of 71 patients of which 58 were...
Use of Leflunomide as a treatment for paediatric chronic uveitis
Leflunomide is a disease modifying anti-rheumatic drug approved for treatment of rheumatoid arthritis and psoriatic arthritis in adult patients. This study reports five illustrative case reports of children using Leflunomide as an adjunct treatment with anti-tumour necrosis factor (TNF) agents...
