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Reduction of severe visual loss and complications following IAC for RB
This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...
Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)
The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...
Cyclosporine A and pterygium fibroblasts
The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...
Comparison of methods of central corneal thickness measurement in glaucoma
This prospective study was done to compare the accuracy and reproducibility of central corneal thickness measured by hand-held and disc-mounted ultrasound pachymeter in glaucoma patients. Sixty-five patients were included in the study. Patients with corneal diseases, corneal astigmatism >3 diopters...
Rituximab as an immunosuppression treatment for thyroid eye disease
Thyroid eye disease is traditionally treated with high dose glucocorticosteroids and surgical orbital decompression, where responses are often inadequate. This medical treatment is centred around symptom control and reduction of thyroid hormone synthesis, not immunosuppression. Rituximab is an anti-CD20 monoclonal...
Association between neuro-ophthalmology signs and chronic ataxia in children
Neuro-ophthalmological signs (N-OS) occur commonly in children with chronic ataxia. This study describes the N-OS and their frequencies, in general and by specific disease aetiology in paediatric patients with chronic ataxia. In total, 184 patients under the age of 17...
Visual outcomes, visual fields and optical coherence tomography in paediatric craniopharyngioma
This study reviews the visual outcomes of ten patients under the age of 18 years with craniopharyngioma. The paper also reviews the correlation between visual field (VF) testing and optical coherence tomography (OCT) examination and evaluates the role of OCT...
Systemic rituximab immunotherapy in the management of primary ocular adnexal lymphoma single institutional experience
Ocular adnexal lymphomas constitute 2% of all non-Hodgkin’s disease and 5-15% of all extranodal lymphomas and are usually localised, low-grade and of B-cell origin. This opens them up to potential treatment with a systemic monoclonal antibody-based drug (rituximab) directed at...
Lower postoperative scar height is associated with increased postoperative trichiasis one year after bilamellar tarsal rotation surgery
Bilamellar tarsal rotation has been a key component of the WHO SAFE approach to blindness from trichiaisis (surgery, antibiotics, facial hygiene, environment). The World Health Organisation (WHO) manual describes the procedure as a full thickness blepharotomy placed 3.0mm above and...
Ointment related granulomas post-blepharoplasty
This is a retrospective review of eight patients who developed granulomatous masses after lower lid blepharoplasty. All patients had sutureless bilateral trans-conjunctival surgery, and lubricating ointment was instilled into the inferior fornix postoperatively for two days. Painless lower lid masses...
Evaluating ocular motor functions
Traditionally orthoptists are specialised in assessing ocular motor disorders. This article introduces the ocular motor score as a new clinical tool for screening and follow-up for children and young adults. The protocol consists of 15 tests such as stereoacuity, strabismus,...
