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Somatostatin protects retinal pericytes

Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...

A case presentation of morning glory disc anomaly and peripapillary staphyloma

The purpose of this paper is to present a case of an 18-month-old girl initially presenting with strabismus. Fixation of the affected eye was intermittent with a relative afferent pupillary defect. A fundus photography of the affected left eye showed...

Comparison of bupivacaine injection vs. mini-tenotomy for small angle deviations

Bupivacaine hydrochloride is an aminoacyltype local anaesthetic. Injection into extraocular muscles elicits a myotoxic response destroying striated muscle fibres but sparing satellite cells, nerves and vessels. Preserved satellite cells proliferate to form new muscle fibres, causing muscle hypertrophy and greater...

Understanding optic nerve head pericytes and glaucoma

The authors provide a comprehensive review of the current understanding of pericytes in the optic nerve head (ONH). Key points include: (1) Pericytes are contractile mural cells that play crucial roles in regulating blood flow, maintaining the blood-brain / blood-retinal...

Discussing treatment modalities for bilateral wet AMD

A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

Webinar will look at impact of menopause on eye health

A BCLA webinar will look at the impact going through the menopause can have on female eye health.

The Preston Rule

The selection, specification and fitting of a spectacle frame necessitates the recording of certain measurements particular to the frame. These measurements are also essential when it is required to manufacture a handmade spectacle frame. Instruments designed to accomplish this task...

My message to future ophthalmology teaching fellows: Organising an effective ophthalmology placement

Globally, teaching ophthalmology during the undergraduate period presents challenges. The time allocated for it is minimal with substandard exposure [1,2]. Additionally, the number of universities mandating formal ophthalmology education has significantly declined [3]. Research supports the observation that doctors in...

A focus on Pakistan’s growing eye care needs: over 43 million patients treated for curable blindness free of charge

With 90% of the world’s visually impaired living in developing countries, Pakistan is no exception to this on-going global healthcare challenge. Despite massive leaps over the last few decades in targeting this issue, the World Health Organisation (WHO) reports that...

Report on preoperative visual acuities of patients from two AMM surgical trips to Magdalena, Northern Bolivia

The Andean Medical Mission (AMM), founded in 2012, recently celebrated 12 years of dedicated service in the Bolivian Amazon, aiming to eliminate avoidable blindness. Over this period, AMM has successfully performed over 1700 surgeries, including for children with congenital or...

Retinoblastoma – the challenges of a rare cancer and the role of international partnerships

Introduction: the global challenge The global burden of retinoblastoma (Rb) is one in 15,000-18,000 live births, which equates to 8000 new cases worldwide each year. The global disparities in Rb outcome represent a paradigm of health inequality worldwide [1]. In...

A three-way partnership between Nigeria, Tanzania and Northern Ireland

VISION 2020 LINKS between Western Health and Social Care Trust (WHSCT), Altnagelvin Area Hospital, Northern Ireland with first ECWA Eye Hospital, Kano, Nigeria and now also with Mbeya Referral Hospital (MRH), Tanzania, have been beneficial to all three partners. From...