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Pioneering eye device restores reading vision to blind eyes

A pivotal European clinical trial of a new electronic eye implant has seen remarkable results. The study, published in the New England Journal of Medicine, showed 84% of participants were able to read letters, numbers and words using prosthetic vision...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Ocular manifestations of multiple sclerosis: an overview

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

Lancet Commission calls for global action on blindness

The Lancet Global Health Commission on Global Eye Health highlights the changing nature of the issues facing eye health professionals worldwide.

Moorfields Lacrimal assessment for nursing & allied professionals study day

This course will educate nurses and allied health professionals on lacrimal examination and investigation. A hands on teaching approach ensures that delegates are able to demonstrate safe and effective lacrimal technique, whilst the patient's perspective as a service user remains...

Pseudostrabismus leading to strabismus

The authors aimed to evaluate the incidence of strabismus in children initially diagnosed with pseudostrabismus and identify risk factors for development of strabismus. This was a retrospective review of 65 patients with a diagnosis of pseudostrabismus; two exo and 63...

N-T asymmetry in tracking eye movements

The current study aimed to quantify and compare the visual tracking responses of two sensory induced strabismic juvenile monkeys during monocular smooth pursuit, ocular following response and optokinetic nystagmus (OKN). Monkey 1 had esotropia and monkey 2 had exotropia. Both...

Structural effects of migraine on the retina

Migraine is a common, chronic, multifactorial neuro-vascular disorder typically characterised by recurrent attacks of disabling headache and autonomic nervous system dysfunction (migraine without aura). Up to one third of patients also have neurological aura symptoms (migraine with aura). The objective...

Choroidal thickness in ocular sarcoidosis by OCT measurement

This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...

Spectral domain OCT vs. confocal scanning laser ophthalmoscope in measuring RNFL thickness

The aim of this prospective study was to compare the retinal nerve fibre layer thickness (RNFL) measurements obtained from the Cirrus optical coherence tomography (spectral domain OCT) with the Heidelberg Retinal Tomograph 3 (HRT3, confocal scanning laser ophthalmoscope). Eighty-eight normal...

Reduction of severe visual loss and complications following IAC for RB

This was a retrospective cohort study of patients with retinoblastoma (RB) who required intra-arterial chemotherapy (IAC) between 2013 and 2015, who had relapsed following systemic chemotherapy. A total of nine patients were included in the study and their ocular complications...